Test
Basic NeuroScience Quiz
Preguntas del test (36)
124. Which one of the following neurotransmitters is not associated with the inhibition of aggressive behavior?
- AA. Dopamine
- BB. Norepinephrine
- CC. Serotonin
- DD. γ-Aminobutyric acid (GABA)
- EE. Glycine
241. Glutamate is not:
- AOne of the two major amino acid neurotransmitters
- BAn inhibitory neurotransmitter
- CInvolved in learning and memory
- DThe primary neurotransmitter in cerebellar granule cells
- EA precursor of GABA
346. Which one of the following statements is true regarding neurotransmitters and anxiety?
- AGABA has nothing to do with anxiety
- BGABA, norepinephrine, and serotonin are associated with anxiety in some way
- CDopamine, glutamate, and histamine are associated with anxiety in some way
- DOnly acetylcholine is associated with anxiety
- EAnxiety can be treated with injection of epinephrine
493. A 25-year-old man is brought to see you because of a change in personality following a boating accident. He fell off of
his boat and landed head first on the dock. He was previously friendly, happy, and high-functioning. Now his speech is
pressured and his mood is labile. He has been irresponsible at work and has been fired from his job. His memory is intact.
Which one of the following brain areas did he damage?- ATemporal lobe
- BOccipital lobe
- CBasal ganglia
- DSubstantia nigra
- EFrontal lobe
597. Which one of the following brain areas is characteristically serotonergic?
- AVentral tegmental area
- BSubstantia nigra
- CNucleus accumbens
- DCerebellum
- ERaphe nuclei
699. A patient comes into the emergency room high on cocaine. Which one of the following brain regions would you expect to
be most active in terms of the reward he is experiencing from the drug?- ANeocortex
- BSubstantia nigra
- CNucleus accumbens
- DLocus ceruleus
- ERaphe nuclei
73. Which one of the following statements is not true regarding receptors?
- ASeven-transmembrane-domain receptors require G proteins to open ion channels
- BIn the ligand-gated ion channel receptor, the channel is built into the complex that binds the ligand
- CSeven-transmembrane-domain receptors have an external NH(2) terminal end and an intracellular COOH terminal end
- DNerve growth factor (NGF) and brain-derived neurotropic factor (BDNF) bind to seven-transmembrane domain-receptors
- EHormones may diffuse into the cell and bind cytoplasmic receptors, which leads to influence over gene expression
833. Which of the following is true regarding norepinephrine (NE) and/or the locus ceruleus?
- ANE is synthesized in the locus ceruleus
- BDopamine is synthesized in the locus ceruleus, NE in the dorsal raphe nuclei
- CAcetylcholine is synthesized with NE in the substantia nigra
- D5-HT is synthesized in the locus ceruleus
- EThe locus ceruleus is the site of the formation of serotonin
935. Which one of the following receptor types is associated with weight gain and sedation?
- A5-HT 2A
- Bα1
- C5-HT 1A
- DH1
- EM1
1037. Which of the following is not a biogenic amine neurotransmitter?
- ADopamine
- Bγ-Aminobutyric acid (GABA)
- CEpinephrine
- DAcetylcholine
- ESerotonin
1144. Melatonin is a neuronal hormone that promotes sleep and is produced in the brain by the:
- APineal gland
- BAnterior pituitary gland
- CPosterior pituitary gland
- DHypothalamus
- EThalamus
1291. Which one of the following is not a second messenger?
- AAdenylyl cyclase
- BcGMP
- CCa2+
- DcAMP
- EInositol triphosphate (IP3)
1395. Which one of the following receptor subtypes is associated with the neurotransmitter glutamate?
- ANicotinic
- BMuscarinic
- Cα1
- Dα-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
- EGABA
1497. Which one of the following statements is true regarding excitatory neurotransmitters?
- AThey open anion channels that depolarize the cell membrane and increase the likelihood of generating an action potential
- BThey open cation channels that hyperpolarize the cell membrane and increase the likelihood of generating an action potential
- CThey open cation channels that hyperpolarize the cell membrane and decrease the likelihood of generating an action potential
- DThey open anion channels that hyperpolarize the cell membrane and decrease the likelihood of generating an action potential
- EThey open cation channels that depolarize the cell membrane and increase the likelihood of generating an action potential
15117. Which one of the following statements is not true regarding chemical signaling between neurons?
- ANeurotransmitter synthesis may be stimulated by influx of Ca2+
- BNE-releasing neurons have presynaptic α receptors, which are involved in a negative feedback system to stop NE release
- COnce dopamine is released into the synaptic cleft it works until it diffuses away or is removed by reuptake mechanisms
- DExocytosis is the process by which neurotransmitter storage vesicles release their contents into the synaptic cleft
- EMonoamine oxidase type B (MAO-B) metabolizes NE and serotonin
16125. Which one of the following ions uses the second ion channel to open during an action potential, acts as a second messenger once in the neuron, activates the release of neurotransmitter, and activates ion channels that allow for influx of other ions that halt the action potential?
- ANa+
- BK+
- CCl−
- DCa2+
- EIP(3)
17127. Which one of the following statements is true regarding inhibitory neurotransmitters?
- AThey open chloride channels that depolarize the cell membrane and increase the likelihood of an action potential
- BThey open cation channels that depolarize the cell membrane and increase the likelihood of an action potential
- CThey open chloride channels that hyperpolarize the cell membrane and increase the likelihood of an action potential
- DThey open chloride channels that hyperpolarize the cell membrane and decrease the likelihood of an action potential
- EThey open potassium channels that depolarize the cell membrane and decrease the likelihood of an action potential
1813. Which one of the following neurotransmitters works as an adjunctive neurotransmitter for glutamate as well as an independent neurotransmitter with its own receptors?
- AGABA
- BNorepinephrine
- CSerotonin
- DDopamine
- EGlycine
1929. Which one of the following neurotransmitters has large numbers of receptors in the spinal cord, is synthesized primarily from serine, and has been the subject of research involving negative symptom reduction in schizophrenia?
- AGABA
- BGlycine
- CSerotonin
- DDopamine
- EGlutamate
2069. Which one of the following brain structures’ dopaminergic neurons have been linked with Tourette’s syndrome and the development of tics?
- ACaudate
- BSubstantia nigra
- CAmygdaloid body
- DFrontal cortex
- EHippocampus
2180. Alcohol, benzodiazepine sedative-hypnotic agents, and barbiturates all predominantly exert their clinical effects on the brain at which one of the following receptor sites?
- ACholinergic nicotinic
- BNMDA
- CGlycine
- DGABA-A
- EGABA-B
2281. An elderly man comes into his doctor’s office with symptoms of dementia and notable loss of executive functioning. Dysfunction of which one of the following brain regions would be most closely associated with the patient’s loss of executive
functioning?- ACaudate nucleus
- BPutamen
- CGlobus pallidus
- DFrontal lobes
- ETemporal lobes
2393. Which one of the following dopaminergic pathways or areas is associated with the antipsychotic effects of the antipsychotic medications?
- ANigrostriatal pathway
- BMesolimbic–mesocortical pathway
- CTuberoinfundibular pathway
- DCaudate nucleus
- EAmygdaloid body
243. Which one of the following is true regarding norepinephrine (NE) and/or the locus ceruleus?
- ANE is synthesized in the locus ceruleus
- BDopamine is synthesized in the locus ceruleus, NE in the dorsal raphe nuclei
- CAcetylcholine is synthesized with NE in the substantia nigra
- Dγ-Aminobutyric acid (GABA) is synthesized in the locus ceruleus
- EThe locus ceruleus is the site of formation of serotonin
2525. The highest rate of synapse formation in the brain takes place during which one of the following time periods?
- AAdolescence
- BWeeks 32 to 35 of gestation
- CWeeks 13 to 26 of gestation
- DWithin the first 6 weeks of gestation
- EAs a toddler
2641. Which one of the following receptor subtypes is associated with the neurotransmitter glutamate?
- ANicotinic
- BMuscarinic
- Cα1
- Dα-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
- EGABA
2771. Which one of the following is not true regarding the N-methyl-d-aspartate (NMDA) receptor?
- AThe NMDA receptor has been linked with learning and memory
- BThe NMDA receptor allows for the passage of potassium only
- CThe NMDA receptor opens only when it has bound two molecules of glutamate and one molecule of glycine
- DThe NMDA receptor can be blocked by physiological concentrations of magnesium
- EThe NMDA receptor can be blocked by PCP
2876. Emotional memory localizes to the:
- AAmygdala
- BHippocampus
- CPrimary auditory cortex
- DNucleus basalis of Meynert
- EPons
2993. Which one of the following drugs is both an opioid agonist and antagonist?
- AAripiprazole
- BNaltrexone
- CBuprenorphine
- DMethadone
- EGabapentin
30102. Which one of the following neurotransmitters localizes predominantly to the basal forebrain and is responsible for memory, attention, and executive functioning?
- ASerotonin
- BNE
- CGABA
- DGlycine
- EAcetylcholine
31108. The GABA-A receptor (the most predominant GABA receptor) is which one of the following
- AA sodium channel
- BA chloride channel
- CA calcium channel
- D. A potassium channel
- EA magnesium channel
32134. Which one of the following structures is most critical to the formation of memory?
- ARight frontal lobe
- BRight parietal lobe
- CThalamus
- DCerebellum
- EHippocampus
33144. Which one of the following answer choices is true regarding aggression?
- AHigh levels of cerebrospinal fluid (CSF) serotonin are associated with increased aggression
- BSerotonin is unrelated to aggression
- CLow levels of CSF serotonin are associated with increased aggression
- DLow levels of CSF serotonin are associated with decreased aggression
- ELow levels of dopamine are associated with increased aggression
34Blocking the H1 receptor will lead to which of the following?
- AWeight gain
- BDry mouth
- COrthostatic hypotension
- DElevated prolactin
- EUrinary retention
35106. Which of the following neurochemical changes would you expect to see in a patient with increased aggression?
- AIncreased serotonin
- BDecreased dopamine
- CDecreased testosterone
- DDecreased GABA
- EDecreased acetylcholine
3643. Which of the following brain pathways starts in the ventral tegmental area and projects to the frontal cortex?
- ATuberoinfundibular pathway
- BNigrostriatal pathway
- CMesolimbic pathway
- DMesocortical pathway
- EVentral amygdalofugal pathway
Información
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- This is a Quiz opposed to Flashcards in order to see how the different "apps" on this website work.
- Autor
- Usuario eliminado
- Idioma
- English
- Visitas
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- Historial
- Creado el 9 dic 2019 · actualizado el 9 dic 2019
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