Once tyrosine kinase is activated, which protein binds?
Phospholipase Cgamma
Phospholipase Cdelta
Phospholipase Calpha
How does tyrosine kinase activate phospholipase cX?
No, really, how'd you think? What else could it POSSIBLY BE
Phosphorylation
What is the function of Phospholipase Cgamma?
PIP3 breakdown
PIP2 breakdown
PIP breadown
What happens to phospholipase cX when it binds to T.K?
It is phosphorylated
It's dephosphorylated
Name the products of PIP breakdown
IP3
DAG
No seriously, how many times have we covered this protein family?
What subunit allows Phospholipase Cgamma to be recruited to the phosphorylated tyrosine kinase?
SH3
SH2
SH4
Most of the phospholipase cgamma's effects are the same as phospholipase Cbeta, which one is different?
PKC activation causes the activation of Na+/H+ pumps
PKC activation causes the activation of Na+/K+ pumps
PKC activation causes the activation of Na+/Cl- pumps
What is the effect of the membrane pump activation?
Cell becomes more alkaline
Cell becomes more acidic
Cell prepares for mitosis
