PIP2 Pathway

Description

Year 2 Quiz on PIP2 Pathway, created by gina_evans0312 on 04/11/2013.
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Quiz by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 over 10 years ago
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Resource summary

Question 1

Question
Once tyrosine kinase is activated, which protein binds?
Answer
  • Phospholipase Cgamma
  • Phospholipase Cdelta
  • Phospholipase Calpha

Question 2

Question
How does tyrosine kinase activate phospholipase cX?
Answer
  • No, really, how'd you think? What else could it POSSIBLY BE
  • Phosphorylation

Question 3

Question
What is the function of Phospholipase Cgamma?
Answer
  • PIP3 breakdown
  • PIP2 breakdown
  • PIP breadown

Question 4

Question
What happens to phospholipase cX when it binds to T.K?
Answer
  • It is phosphorylated
  • It's dephosphorylated

Question 5

Question
Name the products of PIP breakdown
Answer
  • IP3
  • DAG
  • No seriously, how many times have we covered this protein family?

Question 6

Question
What subunit allows Phospholipase Cgamma to be recruited to the phosphorylated tyrosine kinase?
Answer
  • SH3
  • SH2
  • SH4

Question 7

Question
Most of the phospholipase cgamma's effects are the same as phospholipase Cbeta, which one is different?
Answer
  • PKC activation causes the activation of Na+/H+ pumps
  • PKC activation causes the activation of Na+/K+ pumps
  • PKC activation causes the activation of Na+/Cl- pumps

Question 8

Question
What is the effect of the membrane pump activation?
Answer
  • Cell becomes more alkaline
  • Cell becomes more acidic
  • Cell prepares for mitosis
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