Fichas
128, 129 - Bugs with Exotoxins
Fichas del conjunto (77)
- 1Which bacteria with exotoxins inhibit protein synthesis?Corynebacterium diphtheriae
Pseudomonas aeruginosa
Shigella spp.
Enterohemorrhagic E coli (EHEC - 2Inhibit protein synthesis What toxin is associated with Corynebacterium diphtheriae?Diphtheria toxina
*An AB toxin - 3Inhibit protein synthesis What toxin is associated with Pseudomonas aeruginosa?Exotoxin A
*An AB toxin - 4Inhibit protein synthesis What toxin is associated with Shigella spp.?Shiga toxin (ST)
*An AB toxin - 5Inhibit protein synthesis What toxin is associated with Enterohemorrhagic E coli (EHEC)?Shiga-like toxin (SLT)
*An AB toxin - 6Increase fluid secretion What toxin is associated with Enterotoxigenic E coli (ETEC)?Heat-labile toxin (LT)
*An AB toxin
Heat-stable toxin (ST) - 7Increase fluid secretion What toxin is associated with Bacillus anthracis?Edema toxin
*An AB toxin - 8Increase fluid secretion What toxin is associated with Vibrio cholerae?Cholera toxin
*An AB toxin - 9Inhibit phagocytic ability What toxin is associated with Bordetella pertussis?Pertussis toxin
*An AB toxin - 10Inhibit release of neurotransmitter What toxin is associated with Clostridium tetani?Tetanospasmin
*An AB toxin - 11Inhibit release of neurotransmitter What toxin is associated with Clostridium botulinum?Botulinum toxin
*An AB toxin - 12Lyse cell membranes What toxin is associated with Clostridium perfringens?Alpha toxin
- 13Lyse cell membranes What toxin is associated with Streptococcus pyogenes?Streptolysin O
- 14Superantigens causing shock What toxin is associated with Staphylococcus aureus?Toxic shock syndrome toxin (TSST-1)
- 15Superantigens causing shock What toxin is associated with Streptococcus pyogenes?Exotoxin A
- 16Which bacteria with exotoxins Increase fluid secretion?Enterotoxigenic E coli (ETEC)
Bacillus anthracis
Vibrio cholerae - 17Which bacteria with exotoxins inhibit phagocytic ability?Bordetella pertussis
- 18Which bacteria with exotoxins inhibit release of neurotransmitter?Clostridium tetani
Clostridium botulinum - 19Which bacteria with exotoxins Lyse cell membranes?Clostridium perfringens
Streptococcus pyogenes - 20Which bacteria with exotoxins are superantigens causing shock?Staphylococcus aureus
Streptococcus pyogenes - 21What bacteria with exotoxins are associated with the following toxin? Exotoxin AStreptococcus pyogenes
Pseudomonas aeruginosa - 22What bacteria with exotoxins are associated with the following toxin? Toxic shock syndrome toxin (TSST-1)Staphylococcus aureus
- 23What bacteria with exotoxins are associated with the following toxin? Streptolysin OStreptococcus
pyogenes - 24What bacteria with exotoxins are associated with the following toxin? Alpha toxinClostridium perfringens
- 25What bacteria with exotoxins are associated with the following toxin? Botulinum toxinClostridium botulinum
- 26What bacteria with exotoxins are associated with the following toxin? TetanospasminClostridium tetani
- 27What bacteria with exotoxins are associated with the following toxin? Pertussis toxinBordetella pertussis
- 28What bacteria with exotoxins are associated with the following toxin? Cholera toxinVibrio cholerae
- 29What bacteria with exotoxins are associated with the following toxin? Edema toxinBacillus anthracis
- 30What bacteria with exotoxins are associated with the following toxin? Heat-labile toxin (LT)Enterotoxigenic E coli (ETEC)
- 31What bacteria with exotoxins are associated with the following toxin? Heat-stable toxin (ST)Enterotoxigenic E coli (ETEC)
- 32What bacteria with exotoxins are associated with the following toxin? Shiga-like toxin (SLT)Enterohemorrhagic E coli
- 33What bacteria with exotoxins are associated with the following toxin? Shiga toxin (ST)Shigella spp.
- 34What bacteria with exotoxins are associated with the following toxin? Diphtheria toxinCorynebacterium diphtheriae
- 35What is the mechanism for the following bacteria with exotoxins? Corynebacterium diphtheriae (Diphtheria toxin)Inactivate elongation factor
(EF-2) - 36What is the mechanism for the following bacteria with exotoxins? Pseudomonas aeruginosa (Exotoxin A)Inactivate elongation factor
(EF-2) - 37What is the mechanism for the following bacteria with exotoxins? Shigella spp. (Shiga toxin (ST))Inactivate 60S ribosome by removing adenine from rRNA
- 38What is the mechanism for the following bacteria with exotoxins? Enterohemorrhagic E coli (EHEC) (Shiga-like toxin (SLT))Inactivate 60S ribosome by removing adenine from rRNA
- 39What is the mechanism for the following bacteria with exotoxins? Enterotoxigenic E coli (ETEC) (Heat-labile toxin (LT))Overactivates adenylate cyclase (increasing cAMP) leading to increased Cl− secretion in gut and H2O efflux
- 40What is the mechanism for the following bacteria with exotoxins? Enterotoxigenic E coli (ETEC) (Heat-stable toxin (ST))Overactivates guanylate cyclase (increases cGMP) leads to decreased resorption of NaCl and H2O in gut
- 41What is the mechanism for the following bacteria with exotoxins? Bacillus anthracis (Edema toxin)Mimics the adenylate
cyclase enzyme (increased cAMP) - 42What is the mechanism for the following bacteria with exotoxins? Vibrio cholerae (Cholera toxin)Overactivates adenylate
cyclase (increases cAMP) by
permanently activating Gs
leads to increased Cl− secretion in gut
and H2O efflux - 43What is the mechanism for the following bacteria with exotoxins? Bordetella pertussis (Pertussis toxin)Overactivates adenylate cyclase (increasing cAMP) by disabling Gi, impairing phagocytosis to permit survival of microbe
- 44What is the mechanism for the following bacteria with exotoxins? Clostridium tetani (Tetanospasmin)Both are proteases that cleave SNARE (soluble NSF attachment protein receptor), a set of proteins required for neurotransmitter release via vesicular fusion
- 45What is the mechanism for the following bacteria with exotoxins? Clostridium botulinum (Botulinum toxin)Both are proteases that cleave SNARE (soluble NSF attachment protein receptor), a set of proteins required for neurotransmitter release via vesicular fusion
- 46What is the mechanism for the following bacteria with exotoxins? Clostridium perfringens (Alpha toxin)Phospholipase (lecithinase)
that degrades tissue and
cell membranes - 47What is the mechanism for the following bacteria with exotoxins? Streptococcus pyogenes (Streptolysin O)Protein that degrades cell
membrane - 48What is the mechanism for the following bacteria with exotoxins? Streptococcus pyogenes (Exotoxin A)Binds to MHC II and TCR outside of antigen binding site to cause overwhelming release of IL-1, IL-2, IFN-γ, and TNF-α leading to shock
- 49What is the mechanism for the following bacteria with exotoxins? Staphylococcus aureus (Toxic shock syndrome toxin (TSST-1))Binds to MHC II and TCR outside of antigen binding site to cause overwhelming release of IL-1, IL-2, IFN-γ, and TNF-α leading to shock
- 50What is the manifestation of the following bacteria with exotoxins? Staphylococcus aureus (Toxic shock syndrome toxin (TSST-1))Toxic shock syndrome: fever, rash, shock; other toxins cause scalded skin syndrome (exfoliative toxin) and food poisoning (heat-stable enterotoxin)
- 51What is the manifestation of the following bacteria with exotoxins? Streptococcus pyogenes (Exotoxin A)Toxic shock–like syndrome: fever, rash, shock; scarlet fever
- 52What is the manifestation of the following bacteria with exotoxins? Streptococcus pyogenes (Streptolysin O)Lyses RBCs; contributes to β-hemolysis;
host antibodies against toxin (ASO) used to diagnose rheumatic fever (do not confuse
with immune complexes of poststreptococcal glomerulonephritis) - 53What is the manifestation of the following bacteria with exotoxins? Clostridium perfringens (Alpha toxin)Degradation of phospholipids leads to myonecrosis (“gas gangrene”) and hemolysis (“double zone” of hemolysis on blood agar)
- 54What is the manifestation of the following bacteria with exotoxins? Clostridium botulinum (Botulinum toxin)Flaccid paralysis, floppy baby; toxin prevents release of stimulatory (ACh) signals at neuromuscular junctions leads to flaccid paralysis
- 55What is the manifestation of the following bacteria with exotoxins? Clostridium tetani (Tetanospasmin)Spastic paralysis, risus sardonicus, and “lockjaw”; toxin prevents release of inhibitory (GABA and glycine) neurotransmitters from Renshaw cells in spinal cord.
- 56The following is the manifestation of what bacteria with exotoxins? Spastic paralysis, risus sardonicus, and “lockjaw”; toxin prevents release of inhibitory (GABA and glycine) neurotransmitters from Renshaw cells in spinal cord.Clostridium tetani
(Tetanospasmin) - 57The following is the manifestation of what bacteria with exotoxins? Flaccid paralysis, floppy baby; toxin prevents release of stimulatory (ACh) signals at neuromuscular junctions leads to flaccid paralysisClostridium botulinum
(Botulinum toxin) - 58What is the manifestation of the following bacteria with exotoxins? Bordetella pertussis (Pertussis toxin)Whooping cough—child coughs on expiration and “whoops” on inspiration (toxin may not actually be a cause of cough; can cause “100-day cough” in adults)
- 59The following is the manifestation of what bacteria with exotoxins? Whooping cough—child coughs on expiration and “whoops” on inspiration (toxin may not actually be a cause of cough; can cause “100-day cough” in adults)Bordetella pertussis
(Pertussis toxin) - 60What is the manifestation of the following bacteria with exotoxins? Vibrio cholerae (Cholera toxin)Voluminous “rice-water” diarrhea
- 61The following is the manifestation of what bacteria with exotoxins? Voluminous “rice-water” diarrheaVibrio cholerae
(Cholera toxin) - 62What is the manifestation of the following bacteria with exotoxins? Bacillus anthracis (Edema toxin)Likely responsible for characteristic edematous borders of black eschar in cutaneous anthrax
- 63The following is the manifestation of what bacteria with exotoxins? Likely responsible for characteristic edematous borders of black eschar in cutaneous anthraxBacillus anthracis
(Edema toxin) - 64What is the manifestation of the following bacteria with exotoxins? Enterotoxigenic E coli (ETEC) (Heat-liable toxin (LT) and Heat-stable toxin (ST)Watery diarrhea: “labile in the Air (Adenylate cyclase), stable on the Ground (Guanylate cyclase)”
- 65The following is the manifestation of what bacteria with exotoxins? Watery diarrhea: “labile in the Air (Adenylate cyclase), stable on the Ground (Guanylate cyclase)”Enterotoxigenic E coli (ETEC)
(Heat-liable toxin (LT) and Heat-stable toxin (ST)) - 66What is the manifestation of the following bacteria with exotoxins? Enterohemorrhagic E coli (EHEC) (Shiga-like toxin (SLT))SLT enhances cytokine release, causing HUS (prototypically in EHEC serotype O157:H7). Unlike Shigella, EHEC does not invade host cells
- 67The following is the manifestation of what bacteria with exotoxins? SLT enhances cytokine release, causing HUS (prototypically in EHEC serotype O157:H7). Unlike Shigella, EHEC does not invade host cellsEnterohemorrhagic E coli (EHEC)
(Shiga-like toxin (SLT)) - 68What is the manifestation of the following bacteria with exotoxins? Shigella spp (Shiga toxin (ST))GI mucosal damage leads to dysentery; ST also enhances cytokine release, causing hemolyticuremic syndrome (HUS)
- 69The following is the manifestation of what bacteria with exotoxins? GI mucosal damage leads to dysentery; ST also enhances cytokine release, causing hemolyticuremic syndrome (HUS)Shigella spp
(Shiga toxin (ST)) - 70What is the manifestation of the following bacteria with exotoxins? Pseudomonas aeruginosa (Exotoxin A)Host cell death
- 71The following is the manifestation of what bacteria with exotoxins? Host cell deathPseudomonas aeruginosa
(Exotoxin A) - 72What is the manifestation of the following bacteria with exotoxins? Corynebacterium diphtheriae (Diphtheria toxin)Pharyngitis with pseudomembranes in throat and severe lymphadenopathy (bull neck)
- 73The following is the manifestation of what bacteria with exotoxins? Pharyngitis with pseudomembranes in throat and severe lymphadenopathy (bull neck)Corynebacterium diphtheriae
(Diphtheria toxin) - 74The following is the manifestation of what bacteria with exotoxins? Degradation of phospholipids leads to myonecrosis (“gas gangrene”) and hemolysis (“double zone” of hemolysis on blood agar)Clostridium perfringens
(Alpha toxin) - 75The following is the manifestation of what bacteria with exotoxins? Lyses RBCs; contributes to β-hemolysis; host antibodies against toxin (ASO) used to diagnose rheumatic fever (do not confuse with immune complexes of poststreptococcal glomerulonephritisStreptococcus pyogenes
(Streptolysin O) - 76The following is the manifestation of what bacteria with exotoxins? Toxic shock syndrome: fever, rash, shock; other toxins cause scalded skin syndrome (exfoliative toxin) and food poisoning (heat-stable enterotoxin)Staphylococcus aureus
(Toxic shock syndrome toxin (TSST-1)) - 77The following is the manifestation of what bacteria with exotoxins? Toxic shock–like syndrome: fever, rash, shock; scarlet feverStreptococcus pyogenes
(Exotoxin A)
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- El usuario ha eliminado su información de asignaturas Fichas sobre 128, 129 - Bugs with Exotoxins, creado por Usuario eliminado el 15/05/2017.
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- Usuario eliminado · may 2017
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- Creado por Victoria Wright · 11 may 2017
- Copiado por Victoria Wright · 15 may 2017
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