Test
general micro and immunology
Este test tiene tiempo límite, así que se abre en el reproductor de siempre.
Preguntas del test (25)
1.Which of the following statement is correct about viruses?
- Aobligate intracellular parasites and have both RNA or DNA
- Bobligate intracellular organism and have only RNA or DNA
- Cthey replicate by binary fission
- DIcosahedral helical form cannot exist without an envelope
2.A 35 years old man who is HIV antibodies positive and has a CD 4 count of 85 cells. He recently had a seizure and an MRI scan indicates a lesion in the temporal lobe.A brain biopsy specimen reveals multinucleated giant cells with intra-nuclear inclusions.Which of the following is the most likely cause?
- AOncovirus
- Bwestern Equine encephalitis virus
- CCoxsackie virus
- DHerpes Simplex virus
3A 35 year old man who is HIV antibody positive and has a CD 4 count of 30 says “I can not remember the simplest things”.You are concerned about dementia. An MRI indicates several widely scattered lesions in the brain.Over the next 4 months he develops visual field defects,becomes paralysed and dies.Autopsy reveals that many neurons of the brain has lost myeline and contained intra-nuclear inclusions.Electrone microscopy reveals the inclusions contain non-enveloped viruses.Which of the following is the most likely cause?
- AAdenovirus
- BCytomegalovirus
- CJ-C virus
- DCoxsackie virus
4A 12 year old girl had a seizure this morning and was rushed to the hospital. On examination her temperature was 400 C and she had no nuchal rigidity.CT scan revealed no abnormality. A spinal tap was done and the protein and glucose were normal.Gram stain of CSF shows no organism or polymorphs.Routine blood culture and CSF cultures grew no organisms.She was treated with various antibiotics but became comatose and died 2 days later.Autopsy of brain showed eosinophilic inclusion bodies in the cytoplasm of the neurons.Which of the following is the most likely cause?
- APrions
- BRabies virus
- CParvovirus B-19 virus
- DHerpese simplex virus type 1
5Aspergillosis is recognized in tissues by the presence of
- ABudding cells
- BSeptate hyphae
- CMetachromatic granules
- DPseudohyphae
6Which of the following media is used to culture fungi?
- Amac conkey medium
- Bchocolate agar
- Csabouraud`s agar
- Dowenstein jensen mediu
7An AIDS patient with a persistent cough has shown progressive behavioral changes in the past few weeks after visiting a zoo. A CSF sample is collected and encapsulated yeast like organism is observed. What is the most likely organism?
- Aaspergillus
- Bcryptococcus neoformans
- Chistoplasma
- Dpseudomonas aeruginosa
8The mycobacterium tuberculosis Contains complex lipids including Mycolic acids, which property is conferred to the mycobacterium by them?
- AAcid fastness
- BFreunds adjuvant
- CCaseation necrosis
- DCord factor
9Selective media needed for isolation of shigella species can be:
- Ablood agar
- Bss agar
- Cchocolate agar
- Dsabaroud`s agar
10Which of the following is true of Haemophilus influenzae?
- AMost invasive infections occur in infants during the neonatal period
- BThe organism can be readily cultured on sheep blood agar in an environment of elevated CO2
- CMost human infections are acquired from domestic pets
- DInvasive infections are most commonly associated with encapsulated strains
11Listeria monocytogenes shows which of the following characteristics?
- AIt can grow at refrigerator temperatures (4 degree calcius)
- BIt is an extracellular pathogen
- CIt is catalase-negative
- DIt is a gram-negative coccus
12A diagnosis of diphtheria is confirmed by:
- AMicroscopic appearance of organisms stained with methylene blue
- BIsolation of typical organisms from materials such as blood, showing invasiveness
- CDetection of " phage plagues in cultures of suspicious isolates
- DDemonstration of toxin production by a suspicious isolate.
13In association with anaerobic fusiform bacteria gingivo-stomatitis and Vincent’s angina is caused by
- ABorellia burgdoferri
- BBorrelia vincenti
- CLeptospira interogans
- DTreponema carateum
14Spore-forming anaerobic bacteria are usually present as normal flora of colon of animals, which one of them is responsible for causing flaccid paralysis after food poisoning.
- AC. perfringens
- BC. tetani
- CC. botulinum
- DC. difficile
15A 35 years old man with the history of pain and swelling of his axillary lymph nodes, high grade fever, myalgias and generalized weakness. On examination the affected nodes are extremely tender. Pus from the node is sent for evaluation to microbiology lab.Waysonn’s staining of his specimen’s smear shows safety pin appearance of the organism. What is the most probable organism responsible for his illness?
- AYerisinea pestis
- Bfransicella tularensis
- Cpasturella multocida
- Dmycobacterium avium
16Infection with the Malassezia furfur organism causes skin hypopigmentation.It is found most frequently in hot and humid regions. It is also responsible for causing one of the cutaneous mycosis. Infectin with malassezia furfur also causes which of the following disorders:
- Atinea capitis
- Btinea cruris
- Ctinea nigra
- Dtinea versicolor
17Peptic ulcer disease: An ulcer is now known to be the result of an imbalance between aggressive and defensive mechanisms in the stomach and duodenum. Part of that imbalance can be attributed to infection by H. pylori. The organism is
- AGram negative rod, urease negative,oxidase positive
- BGram negative rod,urease positive,curved shaped
- CGram negative rod,urease negative ,curved shaped
- DGram negative rod,oxidase positive ,curved shaped
18which of the following is RNA virus
- AHPV
- BHBV
- CCMV
- DHuman T cell leukemia virus
19the antiphagocytic property of group A strept. is associated with which of the following :
- Astreptolysin S
- BM.protein
- Cpeptidoglycan
- Dhyalurindase
20general steps in viral multiplication cycle are
- Aadsorption , penetration , rep;ication, maturation and release
- Bendocytosis , uncoating , replication , assembly and budding
- Cadsorption , uncaoting , duplication , assembly and lysis
- Dendocytosis , penetration , replication , maturation , exocytosis
21which of the following is associated with a deficiency of third component of complement C3
- Apyogenic infection
- Bimmune complex disease
- CSLE
- Dxeroderma pigmentosum
22which of the following components enchances the binding of antigen antibody complex to macrophages :
- AC1
- BC3a
- CC3b
- DC8
23Naturally acquired active immunity would be most likely acquired through which of the following processes?
- Avaccination
- Bdrinking colostrum
- Cnatural birth
- Dinfection with disease causing organism followed by recovery.
24Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?
- AAntigen
- BVirus
- CHapten
- DAntibody
25The ability of the immune system to recognize self antigens versus nonself antigen is an example of:
- ASpecific immunity
- BTolerance
- CCell mediated immunity
- DAntigenic immunity
Información
- Descripción
- multiple choice question on microbiology for 3rd year medical student
- Autor
- Nada Medhat
- Idioma
- English
- Visitas
- 47
- Etiquetas
- Valoración
- Aún sin valoraciones Valora este test