Test
Reproductive Genetics
Este test tiene tipos de pregunta que se abren en el reproductor de siempre.
Preguntas del test (24)
1Match the genetic sampling technique to the tissue it detects:
Placenta - [blank_start]Chorionic Villus Biopsy[blank_end]
Skin / Urine Cells - [blank_start]Amniocentesis[blank_end]
Blood - [blank_start]Fetal blood sampling[blank_end]- AChorionic Villus Biopsy
- BAmniocentesis
- CFetal blood sampling
2Match the genetic sampling technique to the point in pregnancy at which it can be conducted:
After 11.5 weeks: [blank_start]Chorionic Villus Biopsy[blank_end]
After 16 weeks: [blank_start]Amniocentesis[blank_end]
After 18 weeks: [blank_start]Foetal Blood Sample[blank_end]- AFoetal Blood Sample
- BAmniocentesis
- CChorionic Villus Biopsy
3Non-Invasive Prenatal Testing involves taking a sample of [blank_start]blood[blank_end] from a mother to look for foetal DNA
- Ablood
- Burine
- Chair
- Dthe placenta
- Ethe cervix
4When is the earliest in pregnancy that Non-Invasive Prenatal Testing can be conducted?
[blank_start]8[blank_end] Weeks- A8
5Which two of the following genetic sampling methods involve a 1-2% risk of inducing miscarriage?
- AChorionic Villus Biopsy
- BAmniocentesis
- CFoetal Blood Sample
- DNon-Invasive Prenatal Testing
6Which term describes a genetic change that causes disease?
[blank_start]Mutation[blank_end]- AMutation
7Which term describes a genetic change that does not necessarily predispose to a disease?
[blank_start]Polymorphism[blank_end]- APolymorphism
8There are two main types of Polymorphisms present in humans - name them.
[blank_start]Single Nucleotide Polymorphisms[blank_end]: Single base changes
[blank_start]Copy Number Variations[blank_end]: Insertions or deletions of DNA segments- ASingle Nucleotide Polymorphisms
- BCopy Number Variations
9Which three of the following genetic analysis techniques are used for whole genome sampling?
- AArray CGH
- BFoetal DNA in Maternal Blood
- CPoint Mutation Testing
- DFluorescence in-situ Hybridisation (FISH)
- EQuantitative Fluorescent PCR
- FNext Generation Sequencing
10Which three of the following genetic sequencing techniques are used for targeted genetic sequencing?
- AArray CGH
- BFoetal DNA in Maternal Blood
- CNext Generation Sequencing
- DFluorescence in-situ Hybridisation (FISH)
- EQuantitative Fluorescent PCR
- FPoint Mutation Testing
11Foetal Ultrasound scans are typically carried out first at [blank_start]12[blank_end] weeks then again at [blank_start]20[blank_end] weeks to check for any foetal abnormalities
- A12
- B20
12Which measurement made on foetal ultrasound scanning is used to assess whether the child is likely to have abnormalities such as down's syndrome?
[blank_start]Nuchal[blank_end] Thickness- ANuchal
13The nuchal thickness is thought to be abnormal if it is above [blank_start]6[blank_end]mm
- A6
- B10
- C14
14At around 16 weeks a maternal [blank_start]blood[blank_end] test is conducted to look for biochemical markers of Down Syndrome
- Ablood
15Which Genetic Sequencing Test is used to detect extra or missing chromosomes and is thus most useful in detecting Down Syndrome in a foetus with nuchal thickening?
- AArray CGH
- BNext Generation Sequencing
- CFoetal DNA in Maternal Blood
- DFluorescent In-Situ Hybridisation (FISH)
- EQuantitative Fluorescent PCR
- FPoint Mutation Testing
16Apart from Array CGH, which of the following genetic sequencing tests is also useful in detecting Down Syndrome?
- ANext Generation Sequencing
- BFoetal DNA in Maternal Blood
- CFluorescent In-Situ Hybridisation
- DQuantitative Fluorescent PCR
- EPoint Mutation Testing
17Chorionic Villus Biopsy and Amniocentesis can both be used to detect a wide range of foetal abnormalities whereas generally Non-Invasive Prenatal Testing is only used to detect Down Syndrome
- AVerdadero
- BFalso
18Mrs Blue comes to see you. She is 18 weeks pregnant. A detailed scan has shown that her baby has a cardiac defect: an AtrioVentricular Septal Defect that is commonly seen in Down syndrome.
What is the best first egentic sequencing test?
[blank_start]Array CGH[blank_end]- AArray CGH
19Two acrocentric chromosomes stuck end to end is known as a [blank_start]Robertsonian[blank_end] Translocation
- ARobertsonian
20Non-Invasive Prenatal Testing can also be used to determine the sex of the foetus
- AVerdadero
- BFalso
21[blank_start]Balanced[blank_end] Chromosomal Rearrangement: All of the chromosomal material is present
[blank_start]Unbalanced[blank_end] Chromosomal Rearrangement: Extra or missing chromosomal material- AUnbalanced
- BBalanced
22Unbalanced Chromosomal Rearrangement are better than balanced ones
- AVerdadero
- BFalso
23What is the term given to describe the presence of an abnormal number of chromosomes in a cell? For example, a human cell having 45 or 47 chromosomes instead of the usual 46.
[blank_start]Aneuploidy[blank_end]- AAneuploidy
24Array CGH only detects balanced translocations
- AVerdadero
- BFalso
Información
- Descripción
- Genetics I lecture given as a SURPRISE on the friday of week 2 :)))
- Autor
- Matthew Coulson
- Idioma
- English
- Visitas
- 44
- Etiquetas
- Valoración
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