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Cluster de diferenciación CD1-CD50

Luis Miguel Barajas Castañeda Español 72 fichas

Fichas del conjunto (72)

  1. 1CD1Cortical thymocytes, Langerhans cells, dendritic cells and certain T-cell leukemias.
    Non-peptide antigen presentation to T-cell receptors on NKT cells, marks
  2. 2CD1bCortical thymocytes, Langerhans cells and dendritic cells.
    Non peptide antigen presentation to T-cell receptors on NKT cells.
  3. 3CD1cCortical thymocytes, Langerhans cells, dendritic cells and B-cell subsets.
    Non peptide antigen presentation to T-cell receptors on NKT cells.
  4. 4CD1d R3G1Intestinal epithelial cells, B-cell subsets, cortical thymocytes, dendritic cells and certain T-cell leukemias.
    Non peptide antigen presentation to T-cell receptors on NKT cells.
  5. 5CD1e R2G1Cortical thymocytes, Langerhans cells, dendritic cells and certain T-cell leukemias.
    Non peptide antigen presentation.
  6. 6CD2 SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptorThymocytes, natural killer cells, T- and B-cells.
    Adhesion between T-cells and other cell types and T-cell activation.
  7. 7CD3d T3D, OKT3Mature T-cells and thymocytes.
    T-cell activation signaling and regulation of TCR expression.
  8. 8CD3e T3E, TCREMature T-cells and thymocytes.
    T-cell activation signaling and regulation of TCR expression.
  9. 9CD3g T3GMature T-cells and thymocytes.
    T-cell activation signaling and regulation of TCR expression.
  10. 10CD4Thymocyte subsets, T-helper cells, regulatory T-cells, monocytes and macrophages.
    T-cell activation, thymic differentiation and receptor for HIV.
  11. 11CD5 LEU1Thymocytes, T- and B-cell subsets and B-cell chronic lymphocytic leukemia cells.
    Regulates T-cell: B-cell interactions. Interacts with CD72.
  12. 12CD6 OX52, T12, TP120Thymocytes, T- and B-cell subsets and neuron subsets.
    Thymocyte development, a potential market of T-cell activation.
  13. 13CD7 LEU 9, GP40, TP41Thymocytes, T-cells, natural killer cells and pluripotent hematopoietic stem cells.
    T-cell costimulation. Interacts with SECTM1.
  14. 14CD8a MALThymocyte subsets, cytotoxic T-cells, natural killer cells and dendritic cells subsets.
    Co-receptor for MHC class 1 molecules.
  15. 15CD8b CD8B1Thymocyte subsets and cytotoxic T-cells.
    Co-receptor for MHC class 1 molecules.
  16. 16CD9 P24, 5H9 antigen, MIC3, TSPAN29, GIG2Platelets, pre-B-cells, eosinophils, basophils, activated T-cells, endothelial cells and epithelial cells.
    Cell adhesion and migration, platelet activation and aggregation.
  17. 17CD10 Neprilysin, CALLA, SFE, MME, EPNB- and T-cell precursors, fibroblasts, neurons and bone marrow stromal cells.
    Peptidase, regulates B-cell growth.
  18. 18CD11a Integrin alpha-L, LFA-1A, ITGALLeukocytes, lymphocytes, granulocytes, monocytes and macrophages.
    Intracellular adhesion and costimulation.
  19. 19CD11b Integrin alpha-M, CR3A, ITGAMGranulocytes, monocytes, natural killer cells, T- and B-cells and dendritic cells.
    Cell adhesion, apoptosis and chemotaxis.
  20. 20CD11c Integrin alpha-X, Leu M5, ITGAXMonocytes, macrophages, granulocytes, T- and B-cell subsets.
    Cell adhesion.
  21. 21CD11d Integrin-alpha-D, ADB2, ITGADMyelomonocytic cells, peripheral blood leukocyte subsets and tissue-specialized cells.
    Receptor for ICAM3 and VCAM1. May play a role in atherosclerotic process and phagocytosis of blood-borne pathogens.
  22. 22CD13 Aminopeptidase N, ANPEP, APN, PEPNGranulocytes, monocytes (+ precursors), endothelial cells and epithelial cells.
    Zinc binding metalloproteinase.
  23. 23CD14Monocytes, macrophages (myelomonocytic cells), Langerhans cells and granulocytes.
    Receptor for complex of LPS and LBP.
  24. 24CD15 3-FAL, ELAM 1 ligand, fucosyltransferase, Leu M1Granulocytes, monocytes, neutrophils and eosinophils.
    Cell adhesion. Mediates phagocytosis and chemotaxis.
  25. 25CD16a Fc-gamma RIII-alpha, FCGR3A, FCG3, FCGR3, IGFR3Neutrophils, natural killer cells and macrophages.
    Low affinity Fc receptor. Mediates phagocytosis and ADCC.
  26. 26CD16b Fc-gamma RIII-beta, FCGR3B, FCG3, FCGR3, IGFR3Neutrophils and stimulated eosinophils.
    Low affinity Fc receptor.
  27. 27CD17 LactosylceramideMonocytes, platelets, B-cell subsets, granulocytes, dendritic cells, T-cells, platelets, neutrophils and thrombocytes.
    Lactocyl ceramide. Cell surface glycosphingolipid. May play a role in bacterial phagocytosis.
  28. 28CD18 Integrin beta-2, ITGB2, MFI7Leukocytes.
    Forms the beta 2 chain of CD11a-c, cell adhesion.
  29. 29CD19 B-lymphocyte surface antigen B4, T-cell surface antigen Leu-12B-cells (but not plasma cells) and follicular dendritic cells.
    Regulates B-cell development, activation and differentiation. Signal transduction.
  30. 30CD20 B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, MS4A1T- and B-cell subsets.
    B-cell activation and proliferation.
  31. 31CD21 Complement receptor type 2, CR2, C3DR, Complement C3d receptor, Epstein-Barr virus receptorMature B-cells, follicular dendritic cells and T-cell subsets.
    Signal transduction. Receptor for complement components C3Dd and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220.
  32. 32CD22 SIGLEC2, BL-CAM, T-cell surface antigen Leu-14Mature B-cells.
    B-cell adhesion and signal transduction.
  33. 33CD23 Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Fc epsilon RII, FCER2, CLEC4JMature B-cells, activated macrophages, eosinophils, follicular dendritic cells and platelets.
    Low affinity receptor for IgE, ligand for CD19, CD21 and CD81.
  34. 34CD24 NectadrinB-cells, granulocytes, epithelial cells and monocytes.
    Regulation of B-cell proliferation and differentiation.
  35. 35CD25 Interleukin-2 receptor subunit alpha, IL2RA, TAC antigenActivated T- and B-cells, some thymocytes, pre B-cells, regulatory T-cells, and oligodendrocytes.
    Receptor for IL2.
  36. 36CD26 Dipeptidyl peptidase 4, DPP4 , ADABP, ADCP2Mature thymocytes, T-cells (upregulated on activation), activated B-cells, natural killer cells, epithelial cells and macrophages.
    Exoprotease. HIV pathogenesis.
  37. 37CD27 TNF receptor superfamily member 7, TNFRSF 7, CD27L receptor, T14T-cells, medullary thymocytes, B-cell subsets and natural killer cells.
    Costimulation of B- and T-cell activation.
  38. 38CD28 TP44Most T-cells, thymocytes, plasma cells, natural killer cells and activated B-cells.
    Costimulation of T-cells. Induces T-cell activation and survival, interleukin-2 production, T-helper type 2 cell development and clonal expansion.
  39. 39CD29 Integrin beta-1, ITGB1, Fibronectin receptor subunit beta, FNRBLeukocytes.
    Interacts with CD49a in VLA-1 integrin. Lymphocyte and endotelial adhesion, lymphocyte trafficking and transvascular migration. Promotes or inhibits apoptosis (depending on stimulus).
  40. 40CD30 TNF receptor superfamily member 8, TNFRSF8, Ki-1 antigenActivated T- and B-cells, monocytes, activated natural killer cells and Reed-Sternberg cells.
    Regulates lymphocyte proliferation and cell death. Has a critical role in the pathophysiology of Hodgkin’s disease and other CD30+ lymphomas.
  41. 41CD31 Platelet endothelial cell adhesión molecule, PECAM1Monocytes, platelets, granulocytes, endothelial cells, lymphocyte subsets and epithelial cells.
    Cell adhesion. Plays a key role in leukocyte trafficking across endothelium
  42. 42CD32 Fc gamma RII, FCGR2A, FCGR2BB-cells, monocytes, granulocytes, platelets and endothelial cells.
    Regulation of B-cell function. Induces phagocytosis and mediator release.
  43. 43CD33 Sialic acid-binding Ig-like lectin 3, SIGLEC3Monocytes, granulocytes, mast cells and myeloid progenitors.
    Lectin activity and adhesion. A receptor that inhibits the proliferation of normal and leukemic myeloid cells.
  44. 44CD34Hematopoietic stem cells and progenitors and capillary endothelial cells.
    Cell adhesion (via L-selectin). Possible role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracelular matrix or directly to stromal cells.
  45. 45CD35 Complement receptor type 1, C3b/C4b receptorErythrocytes, B-cells, monocytes, neutrophils, eosinophils, follicular dendritic cells and T-cell subsets.
    Receptor for complement components C3b and C4b. Mediates adhesión and phagocytosis.
  46. 46CD36 Platelet glycoprotein 4, Fatty acid translocase, Glycoprotein IIIb GP3B, GP4Platelets, monocytes, macrophages, endothelial cells and thyroid precursors.
    Scavenger receptor preferentially found within lipid rafts. Mediates adhesion and phagocytosis.
  47. 47CD37 Tetraspanin 26, TSPAN26Mature B-cells and myeloid cells. Low level of expression in T-cells, granulocytes and monocytes.
    Signal transduction. Regulates T-cell proliferation.
  48. 48CD38 ADP ribosyl cyclase 1Variable expression levels on most hematopoietic and some non-hematopoietic cells. High levels on plasma cells, early T- and B-cells, activated T-cells and germinal centre B-cells.
    Regulates cell activation, proliferation and adhesion.
  49. 49CD39 NTPDase 1, ENTPD1Macrophages, Langerhans cells, dendritic cells, activated B-cells, natural killer cells and microglial cells.
    B-cell adhesion. Protects activated cells from lysis.
  50. 50CD40 TNF receptor superfamily member 5, TNFRSF5B-cells, monocytes, macrophages, follicular dendritic cells, endothelial cells, fibroblasts and keratinocytes.
    Costimulation of B-cell growth. Differentiation and isotype switching.
  51. 51CD41 Integrin alpha-IIb, GPalpha IIb, ITGA2B, GP2BPlatelets and megakaryocytes.
    Platelet activation and aggregation.
  52. 52CD42a Platelet glycoprotein IX, GP9Platelets and megakaryocytes.
    Platelet adhesion and aggregation. Amplifies platelet response to thrombin
  53. 53CD42b Platelet glycoprotein Ib alpha chain, GP1BAPlatelets and megakaryocytes.
    Platelet adhesion and aggregation.
  54. 54CD42c Platelet glycoprotein Ib beta chain, GP1BBPlatelets and megakaryocytes.
    Platelet adhesion and aggregation.
  55. 55CD42d Platelet glycoprotein V, GP5Platelets and megakaryocytes.
    Platelet adhesion and aggregation.
  56. 56CD43 Leukosialin, Galactoglycoprotein, Leukocyte sialoglycoprotein, SPNLeukocytes (except resting B-cells). Low expression in platelets.
    Anti-adhesion. Binds CD45 to mediate adhesion.
  57. 57CD44 Epican, HUTCH-I, LHR, PGP-1, ECMR-IIIMost lymphohematopoietic cells.
    Leukocyte rolling, homing and aggregation. Adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. Important in epithelial cell adhesion (cell-cell and cell-matrix) to hyaluronate in basement membranes, and maintaining polar orientation of cells.
  58. 58CD45 Leukocyte common antigen, L-CA, PTPRCHematopoietic cells (not erythrocytes and platelets).
    Critical for B- and T-cell receptor mediated activation. Also required for thymic selection.
  59. 59CD45RAB- and naïve T-cell subsets, monocytes and medullary thymocytes.
    Critical for B- and T-cell receptor mediated activation. Also required for thymic selection.
  60. 60CD45RBT-cell subsets, B-cells, monocytes, macrophages, granulocytes, dendritic cells and natural killer cells.
    Critical for B- and T-cell receptor mediated activation.
  61. 61CD45RCB-cells, natural killer cells, CD8+ T-cells, CD4+ T-cell subsets, medullary thymocytes, monocytes and dendritic cells.
    Critical for B- and T-cell receptor mediated activation.
  62. 62CD45ROActivated T-cell subsets, memory B- and T-cell subsets, monocytes, macrophages, granulocytes, cortical thymocytes and dendritic cell subsets.
  63. 63CD46 Membrane cofactor protein, TLX, MCPUbiquitous except erythrocytes.
    Co-factor for factor 1 proteolytic cleavage of C3b and C4b. Sets protective barrier threshold against inappropriate complement activation.
  64. 64CD47 Integrin associated protein, MER6Hematopoietic cells, epithelial cells, endothelial cells and mesechymal cells.
    Adhesion. A marker of self which binds to SIRP alpha inhibitor receptor on macro and dendritic cells to inhibit phagocytosis. Regulates chemotaxis and activation of leukocytes.
  65. 65CD48 BLAST1, BCM1Leukocytes.
    Cell adhesion and T-cell costimulation.
  66. 66CD49a Integrin alpha-1, VLA-1, ITGA1Activated T-cells, monocytes, melanoma cells and endothelial cells.
    Adhesion and embryo development.
  67. 67CD49b Integrin alpha-2, VLA-2 subunit alpha, ITGA2Platelets, B-cells, monocytes, activated T-cells, epithelial cells, endothelial cells, natural killer cell subsets and megakaryocytes.
    Adhesion and platelet aggregation. Receptor for echovirus 1.
  68. 68CD49c Integrin alpha-3, VLA-3 subunit alpha, ITGA3Most adhesion cell lines. Low expression on B- and T-cells.
    Adhesion and signal transduction.
  69. 69CD49d Integrin alpha-4, VLA-4 subunit alpha, ITGA4B- and T-cells, thymocytes, monocytes, eosinophils, basophils, natural killer cells, mast cells, dendritic cells and erythroblastic precursors.
    Adhesion, cell migration, homing and activation.
  70. 70CD49e Integrin alpha-5, VLA-5, ITGA5Thymocytes, T-cells, monocytes, platelets, early and activated B-cells, endothelial cells and epithelial cells.
    Adhesion, regulation of cell survival and apoptosis.
  71. 71CD49f Integrin alpha-6, VLA-6, ITGA6Memory B-cells, T-cells, thymocytes, monocytes, platelets, megakaryocytes, epithelial cells, endothelial cells and cytotrophoblasts.
    Embryogenesis, adhesion and cell migration.
  72. 72CD50 ICAM3Leukocytes, thymocytes, Langerhans cells, endothelial cells, B- and T-cells, granulocytes and monocytes.
    Adhesion and costimulation.

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Descripción
Se muestra el CD con el nombre común, si es que aplica. La platilla muestra en la parte superior las células en que se expresa y en la parte inferior la función.
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