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HPA - Lactulose

Usuario eliminado El usuario ha eliminado su información de asignaturas Inglés 13 fichas

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  1. 1What is it?An osmotic laxative
  2. 2Trade namesActilax, Duphalac, Genlac, Lac-Dol, Lactour
  3. 3Pharmacological classGlycoside
  4. 4IndicationsChronic constipation
    hyperammonemia ( caused by hepatic encephalopathy)
  5. 5ActionProduces an osmotic effect in colon; resulting distension promotes peristalsis. Also decreases blood ammonia level by drawing ammonia from circulation into the colon and through the GIT
  6. 6Therapeutic effectsSoftens stools and removes ammonia from circulation
  7. 7Absorption and distributionABSORPTION: poorly absorbed by GIT
    DISTRIBUTION: primarily in the colon
  8. 8Metabolism & excretionmetabolised in the colon by enteric bacteria. Fecal excretion
  9. 9Half life1.7 - 2 hours
  10. 10PrecautionContraindicated in individuals on low-galactose or lactose-free diets
    Use cautiously in individuals with DM
    Be prepared to replace fluid loss
  11. 11Side effectsAbdominal cramping, flatulence, nausea and vomiting, diarrhoea, dehydration and electrolyte disturbances
  12. 12InteractionsAntacids, antibiotics: decreased effectiveness of lactulose. Avoid use together.
  13. 13EducationInstruct patient not to take other laxatives
    Encourage person to exercise, as tolerated
    Advise patient to notify prescriber if diarrhoea occurs
    Educate patient regarding dietary fiber
    Tell patient to keep up fluids

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El usuario ha eliminado su información de asignaturas Fichas sobre HPA - Lactulose, creado por Usuario eliminado el 10/06/2018.
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Historial
  • Creado por Em J · 10 jun 2018
  • Copiado por Em J · 10 jun 2018
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