Fichas
Pathophysiolgy of Atheroclerosis
Fichas del conjunto (15)
- 1Risk Factors for atherosclerosis?Age, Smoking, Lack of exercise, High cholestrol diet,
- 2Layers of vessel wall?
- 3Where is cholesterol synthesised?Liver
- 4Main reason for atherosclerosis formation is endothelial dysfunction, how does this happen?smoking
hypertension - 5Where does atherosclerosis mainly occur?Areas where disturbance in blood flow occurs - bifurcation, branches off blood vessel, low lamina flow.
- 6What lipoprotein carries cholesterol from the liver to the peripheral tissues?Low Density Lipoprotein
- 7What does the high density lipoprotein do?Carry excess cholesterol from the 'overflow' situation in periphery back to the liver.
- 8When in excess LDL can go into the intima and become oxydised - what is the effect of this?oxydised LDL is pro-atherogenic
- 9What does a macrophage become once it ingests lipid?Foam cell
- 10Function of cholesterol in the body?precursor for steroidal hormones
precursor for Vit D3
waterproofing of epidermis (skin)
component of cell membranes - 11When endothelial cell is damaged what does it release?Van Willerband Factor
-act like hooks which connect with platelets (form platelet plug) - 12What causes the inflammation?Coagulation (platelet plug)
LDL's - 13How does the fatty streak formation form?Continued LDL deposition below the tunica intima
- 14What do the macrophages do?Engulf LDL and become foam cells
- 15Symptoms of atherosclerosis?Depends which vessel
-coronoray artery disease (angina with activity)
-claudication (pain in peripheral with activity, ischemia)
-brain (TIA)
Información
- Descripción
- undergraduate Atherosclerosis Fichas sobre Pathophysiolgy of Atheroclerosis, creado por Jeni Thomas el 05/05/2013.
- Creado por
- Jeni Thomas · may 2013
- Actualizado
- 19 feb 2016
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