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| Question | Answer |
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Signs of Uveitis |
| What is the most common form of Acute Uveitis | Anterior Acute Uveitis accounts for 75% of all cases of intraocular inflammation. Moorfields Manual |
| HLA-B27 and Acute Anterior Uveitis are associated in __ % of cases. | 60% Moorfields Manual |
| Symptoms of Acute Anterior Uveitis | Redness, Pain, Photophobia. Usually unilateral but may be simultaneously or sequentially bilateral Moorfields Manual |
| Ocular Signs of Uveitis | Anterior: Injection Conjunctival (pred. perilimbal) Flare (Grade 0-4) and Cells (Grade 1-5) Keratic Precipitates (fine and small or "mutton fat") Fibrin, Hypopyon, Iris abnormalities (synechiae, atrophy, nodules) Posteriorly: Few anterior vitreous cells and cystoid macular edema. Moorfields Manual |
| HLA-B27 (+) disorders | juvenile rheumatoid arthritis ankylosing spondylitis, reactive arthritis, anterior uveitis Reiter's Syndrome Psoriatic Arthritis Inflammatory Bowel Disease Moorfields Manual |
| Acute Anterior Uveitis Investigations Criteria | Recurrent Bilateral Poorly Responsive Disease Suggestive Etiology Moorfields Manual |
| Acute Anterior Uveitis Investigations | Chest X Ray Serum ACE Syphilis Serology Serum HLA B-27 If VA <20/60 and no cause, FAG, OCT Moorfields Manual |
| Acute Anterior Uveitis Duration | Several days to 6 weeks. Less than 3 months by definition. Moorfields Manual |
| Acute Anterior Uveitis Treatment | Cycloplegia, Intensive Topical Steroids (Dexa) Moorfields Manual |
| Chronic Anterior Uveitis is associated with HLA-B27 | False Moorfields Manual |
| A chronic anterior Uveitis is abitrarily defined as an anterior uveitis persisting for >3 months | True Moorfields Manual |
| Chronic Anterior Uveitis may be asymptomatic | True, or present with only blurred vision Moorfields Manual |
| Herpetic Uveitis is a type of Chronic Anterior Uveitis | True Moorfields Manual |
| Fuch's Heterochromic Cyclitis features | White eye, translucent round or stellate keratic precipitates, heterochromia (variable), iris stromal atrophy, PS are absent; cataract is common; raised IOP (25%) vitreous cells and floaters may be considerable, Cystic Macular Edema is rare. Moorfields Manual |
| B cells: A. require the presence of a compatible antigen—presenting cell to recognize a specific antigen. B. produce antibodies. C. are a form of leukocyte. D. mature in the bone marrow of mammals. E. are derived from bone marrow stem cells. | A B cells are able to recognize antigens that have not been presented or processed by other cells. |
| T cells: A. express surface markers such as CD4 or CD8. B. may be “helper” or cytotoxic cells. C. may be “natural killer” cells. D. usually express T cell antigen receptors alpha or beta. E. are “educated” in the thymus. | C Natural killer cells represent a separate group of lymphocytes that lack both immunoglobulins (as in B cells) and antigen receptors (i.e. TCR, as in T cells). |
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