Lecture 3 solubility and dissolution 1

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Flashcards on Lecture 3 solubility and dissolution 1, created by jenny schneider on 31/07/2014.
jenny schneider
Flashcards by jenny schneider, updated more than 1 year ago
jenny schneider
Created by jenny schneider almost 10 years ago
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Question Answer
What is a solution a molecular dispersion of two or more components
if a drug is dissolved in water, which s the solute and which is the solvent? drug is solute and water is the solvent
besides solid in water, what other types of solutions exist? gas in liquid liquid in liquid solid in solid
What are the three steps in dissolution of solid in liquid? solute molecule breaks away from lattice cavity must be made in the solvent solute molecule placed in the cavity of the solvent
What is a saturated solution? solute is dissolved at the limit of solubility at a certain temperature
what is a supersaturated solution? supersaturation is a state of a solution that contains more of the dissolved material than could be dissolved by the solvent under normal circumstances
True or False if the solute-solvent forces are strong enough to compensate for the forces that are broken, then it is likely that the solid will dissolve in a solvent True
True or False The overall heat exchanged in dissolution process is called entropy False It is the heat of solution
What effect will heating the solvent have on dissolution of a drug which has a negative heat of solution? less dissolved at higher temperature
What effect will heating solvent have when a drug has a positive heat of solution? it will increase solubility
True or False If a drug dissolving in solvent has negative heat of solution, we have an endothermic process False it is an exothermic process
What is the dielectric constant measure of the influence by the solvent on energy required to separate two oppositely charged bodies
Which of the following solvents will have the highest dielectric constant: water alcohol benzene water as it is the most polar
If we have a polar drug, which solvent will it best dissolve in? water or benzene water
Alcohol has a lower dielectric constant than water and is classed as semi-polar solvent True or False True
Write the Noyes-Whitney equation (used to describe rate of dissolution) dM/dt= DA(Cs-C)/h
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