117352
Description
Flashcards by Bhavi Mistry, updated more than 1 year ago
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Created by Bhavi Mistry
almost 11 years ago
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| Question | Answer |
| Metformin | 1st line treatment + liver --> - GNG SE: GI disturbance, lactic acidosis |
| Sulphonureas | 1st line treatment +SU Rs, K+ATP, +B cells -> Increased insulin release SE: Hypoglycaemia and weight gain |
| Insulin | Late stage treatment Increases glucose uptake (liver, muscle, fat) SE: hypoglycaemia and weight gain |
| Thiazolidine diones (Rosiglitazone/Avonida) | +PPAR gamma increasing gene transcription of Insulin Rs in fat, liver and muscle, increases insulin sensitivity, reduces FFAs in circulation SE: CVD? |
| Acarbose | alpha glucosidase in intestine SE: GI disturbance |
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