Integrated Cardiopulmonary Pharmacology Third Edition Chapter 4

Alisha Kircheis
Flashcards by Alisha Kircheis, updated more than 1 year ago
Alisha Kircheis
Created by Alisha Kircheis over 6 years ago
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Chapter 4 terms

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Question Answer
Stability Tendency of an aerosol to remain in suspension.
Aerosol Suspension of liquid or solid particles in a gas.
Spacer Reservoir device used with aerosol delivery devices such as MDI's to optimize aerosol drug delivery.
Aerosol therapy delivery of aerosol particles into the respiratory system for therapeutic purposes.
Chlorofluorocarbons (CFC's) Older propellant for MDI's that damage the ozone layer and are reactive in some patients so they are currently banned.
Deposition Aerosol particles falling out or "raining out" of suspension.
Penetration How deep the aerosol particles travel into the respiratory system.
Small Volume Nebulizer (SVN's) A medicated aerosol delivery device that uses a gas powered source to form and deliver the aerosol continuously over a period of usually 8-12 minutes.
Ultrasonic Nebulizer Aerosol delivery device that provides increased speed and capacity while minimizing noise.
Micron One- millionth of a meter, the order of magnitude of how small these aerosol particles are.
Metered dose Inhaler (MDI's) A medicated aerosol delivery device that delivers measured doses (metered puffs) of aerosol from a small gas powered canister.
Medicated aerosol Medicine that has been made into an aerosol to be delivered into the respiratory system.
Inertial Impaction The impacting of aerosol particles on airway walls because of inertial energy.
Hydrofluoroalkanes (HFA's) Replacing CFC's as metered dose inhalant (MDI) propellants, because they do not damage the ozone layer and are not as reactive in patients.
Dry powder inhaler (DPI's) Medicated aerosol delivery device that delivers a powdered (solid) aerosol to the respiratory system.
Mucolytics Breaks down secretions to clear the lungs. Sometimes instilled directly into the lungs in liquid form via the endo-tracheal tube or bronchoscope. Common drug: acetylcysteine (mucomyst)
Antimicrobials Aerosolized antibiotics and antiviral agents to fight both bacterial and viral infections. Common drugs: gentamicin, amphotericin B, ribavirin, pentamidine.
Nasal Decongestants Nasal spray, OTC metered spray, produce larger particles, powerful vasoconstrictors, can increase blood pressure. Common Drugs: neo-synephrine, oxymetazoline.
Corticosteroids Control asthma and prevent or decrease severity of attack, backbone med used to treat persistent asthma. Controls airway inflammation for improved lung function and a decreased need for short acting bronchodilators. Common Drugs: qvar, vanceril, flovent, azmacort.
Mast cell stabilizers Desensitizes the allergic response for asthma attacks. Common Drugs: cromolyn sodium and nedocromil sodium.
Bronchodilators Enlarge the diameter of the airway and relaxes the smooth muscle. Common Drugs: albuterol (proventil), ipratropium (atrovent), pirbuterol (maxair), salmeterol (serevent).
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