Teratogens-Effects on fetus

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Rewise MD
Flashcards by Rewise MD, updated more than 1 year ago
Rewise MD
Created by Rewise MD almost 9 years ago
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Resource summary

Question Answer
ACE inhibitors Renal damage renal dysplasia
Alcohol Fetal Alcohol Syndrome
Alkylating agents Absence of digits Cleft palate Renal agenesis
Aminoglycosides CN VIII toxicity
Anticonvulsants Cleft lip and palate
Cocaine Abnormal fetal development Fetal addiction Low-birth weight Placental abruption
Diethylstilbestrol (DES) Vaginal clear cell adenocarcinoma Other cervical, ovarian, and uterine abnormalities
Folate antagonists Neural tube defects myelomeningocele
Lithium Ebstein's anomaly atrialized right ventricle
Maternal diabetes Caudal regression syndrome sirenomelia renal dysplasia or aplasia imperforate anus
Phenytoin Cleft lip and palate Congenital heart defects
Potassium iodide Congenital goiter or hypothyroidism Cretinism
Nicotine Premature delivery Low birth weight Intrauterine growth retardation ADHD
Tetracyclines Discolored/stained teeth
Thalidomide Gastrointestinal atresia Absence or malformation of external ear Phocomelia "seal" limbs
Valproate Inhibits intestinal folate absorption leading to neural tube defects Cleft lip Renal defects
Vitamin A/isotretinoin Spontaneous abortions Cleft palate Cardiac abormalities Eye and external abnormalities
Warfarin Bone deformities femur, vertebral, and calcaneus show stippled appearance on X-ray Fetal hemorrhage Abortion Spasticity and seizures
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