2973116
Description
Flashcards by Marinescu Mircea, updated more than 1 year ago
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Created by Marinescu Mircea
almost 9 years ago
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| Question | Answer |
| SCLERODERMIA Caracteristici: | • vasculopatie functionala si structurala • fibroza, lez. degenerative piele, org. interne |
| Epidemiologie • Prevalenta- • Incidenta • Frecventa >F | 4 cazuri /1milion(1975) ; 126 cazuri/1milion dupa 1975 18-29 cazuri/1 milion/an F/B=3/1 |
| • FACTORI MEDIU- | uleiuri industriale hidrocarburi, pulberi siliciu medicamente, infectii |
| TERENUL GENETIC | HLA DR2, DR3 anomalii cromozomiale gena fibrilina I |
| FACTORI IMUNI | AAN, TCD4+, IL2 reactie grefa contra gazda (microchimerism fetal) |
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