3514361
Description
Flashcards by whospiltmybeer13, updated more than 1 year ago
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Created by whospiltmybeer13
over 8 years ago
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| Question | Answer |
| Psychopharmacology | the study of effects of drugs on the nervous system and on behavior |
| Drug effect | the changes a drug produces in an animal's physiological processes and behavior |
| Site of action | A location at which molecules of drugs interact with molecules located on or in cells of the body, thus affecting some biochemical processes of these cells |
| Pharmacokinetics | the process by which drugs are absorbed, distributed within the body, metabolized and excreted |
| Intravenous (IV) injection | injection of a substance directly into a vein |
| Intraperitoneal (IP) injection | Injection of a substance into the peritoneal cavity - the space that surrounds the stomach, intestines, liver, and other abdominal organs |
| Intramuscular (IM) injection | injection of a substance into a muscle |
| Subcutaneous (SC) injection | injection of a substance into the space beneath the skin |
| oral administration | administration of a substance into the mouth so that it is swallowed |
| Sublingual administration | administration of a substance by placing it beneath the tounge |
| Intrarectal administration | administration of a substance into the rectum |
| Inhalation | administration of a vaporous substance into the lungs |
| Topical administration | administration of a substance directly onto the skin or mucous membrane |
| Intracerebral administration | administration of a substance directly into the brain |
| Intracerebroventricular (ICV) administration | administration of a substance into one of the cerebral ventricles |
| Dose-response curve | a graph of the magnitude of an effect of a drug as a function of the amount of drug administered |
| Therapeutic index | the ratio between the dose that produces the desired effect in 50% of the animals and the dose that produces toxic effects in 50% of the animals |
| Affinity | the readiness with which two molecules join together |
| Tolerance | A decrease in the effectiveness of a drug that is administered repeatedly |
| Sensitization | an increase in the effectiveness of a drug that is administered repeatedly |
| Withdrawal symptom | the appearance of symptoms opposite to those produced by a drug when the drug is administered repeatedly and then suddenly no longer taken |
| Placebo | an insert substance that is given to an organism in lieu of a physiologically active drug; used experimentally to control for the effects of mere administration of a drug |
| Antagonist | a drug that opposes or inhibits the effects of a particular neurotransmitter on the post-synaptic cell |
| Agonist | a drug that facilitates the effects of a particular neurotransmitter on the post-synaptic cell |
| Direct agonist | a drug that binds with and activates a receptor |
| Receptor blocker | a drug that binds with a receptor but does not activate it; prevents the natural ligand from binding with the receptor. |
| Direct antagonist | a synonym for receptor blocker |
| Noncompetitive binding | binding of a drug to a site on a receptor; does not interfere with the binding site for the principle ligand |
| Indirect antagonist | a drug that attaches to a binding site on a receptor and interferes with the action of the receptor; does not interfere with the binding site for the principle ligand |
| Indirect agonist | a drug that attaches to a binding site on a receptor and facilitates the action of the receptor; does not interfere with the binding site for the principle ligand |
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