DIURETICS

Lav Patel
Flashcards by Lav Patel, updated more than 1 year ago
Lav Patel
Created by Lav Patel over 5 years ago
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medchem

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Question Answer
ACETAZOLAMIDE Used with pilocarpine for better drainage oral Carbonic anhydrase inhibitor used for open angle glaucoma 250-1g/day
METHAZOLAMIDE Birth defexts in rats (at 40x greater dose) 200-300mg TID limited in utility can be used for altitude sickness causes hypokalemia
FUROSEMIDE Very common HTN treatment treats congestive heart failure decrease in blood volume reduce edema compete with uric acid for excretion (causes hyperurocemia) causes hyperkalemia lose mg2+ causes hypobulemia (abnormally decreased blood volume) 20-80mg for max diuresis
BUMETANIDE More potent than furosemide 0.5 to 2 mg for max diuresis elevated risk for autotoxicity (all loop diuretics) lower chance of urocemia because its more potent
Torsemide 5-20mg (2-4x more potent than furosemide)
ETHACRYNIC ACID IF a person is sensitive to sulfa abx there is a chance they will be sensitive to diuretics with sulfa this is used for those patients sharp dose response curve (all or nothing no gradients)
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