PHAR 5902 Breast Cancer

Question	Answer
Incidence of Breast CA	Incidence is 1:8. 2nd most common cause of CA mortality in women (lung CA #1)
Risk factors of Breast CA	- woman (ESTROGEN and Progesterone) - age (esp >50) - family history - previous breast Ca - early menarche, late menopause, nulliparity - BRCA 1/2 gene mutations: 50-85% lifetime risk of breast Ca - HRT - radiation - dense breasts OVER 70% OF BREAST CA OCCURS IN WOMEN WITHOUT IDENTIFIABLE RISKS
Where does breast Ca typically start?	- Cells that line the ducts: DUCTAL CARCINOMA - May start in the lobules: LOBULAR CARCINOMA
Screening Recommendations	- 50-69 yo: Mammogram q 2 years Other ages specific to risk
What is triple assessment?	- examination - imaging (mammogram and/or ultrasound) - needle biopsy
Describe stages 0-4 of Breast Ca	Stage Description 0 There are two kinds of stage 0 breast cancer: Ductal carcinoma in situ (DCIS): Abnormal cells lining milk duct and have not spread outside the duct. Lobular carcinoma in situ (LCIS): Abnormal cells lining lobule NOT CONSIDERED CA 1 Tumor is 2 cm or smaller and the ca has not spread outside breast. 2 Tumor is 2 to 5 cm, or ca has spread to the lymph nodes, or both. 3 Ca has spread to the lymph nodes and may have spread to nearby tissues. 4 Ca has spread to distant parts of the body.

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	Created by Jennifer Melissa Whyte over 1 year ago