Cancer Gene therapy

Question	Answer
There are three categories of genes that may be involved in the causation of cancer	Oncogenes; Tumour suppressor genes; Modifying genes
oncogenes	growth stimulating genes
Tumour suppressor genes	are growth inhibitory genes
Modifying genes	broad spectrum of functions, alleles of which can modify the individual predisposition to cancer
suicide gene therapy	toxic substances incorporated into DNA during synthesis leading to fragmentation
Oncolytic viruses	Viruses that replicate selectively in cancer cells vs normal cells Cancer cells inactivate interferon pathway or mutate tumour suppressor genes, enabling viral replication to proceed When they replicate, they lyse host cells

Resource summary

	Created by lumen7 about 11 years ago