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Pyruvate Carboxylase & PEPCK

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Year 2 (Gluconeogenesis) Flashcards on Pyruvate Carboxylase & PEPCK, created by gina_evans0312 on 30/03/2014.
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Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 about 10 years ago
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Resource summary

Question Answer
Pyruvate Carboxylase- Requirements Biotin and Mg2+
Pyruvate Carboxylase- Pyruvate, ATP & HCO3 --> OAA, ADP & Pi
Pryruvate Carboxylase- Activators Acetyl CoA & Pyruvate
Pyruvate Carboxylase- Inhibitors Calcium, glutatmate & ATP
Increasing Pyruvate Carboxylase Activity- Short Term Increase enzyme activity through allostery
Increasing Pyruvate Carboxylase Activity- Long Term Make more Pyruvate Kinase
PEPCK- OAA + GTP PEP + GDP + CO2
PEPCK- Control No allosteric/covalent
PEPCK - Activation Glucagon, cAMP & Diabetes (switched off by insulin)
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