238585
Description
Mind Map by suheiry.14, updated more than 1 year ago
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Created by suheiry.14
over 12 years ago
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Acute Leukemia
- Definition
- Neoplasia de immature
cells (Blasts) >20%
- >WBC's,
<RBC's,
platelets,
neutrophiles
- >WBC's,
<RBC's,
platelets,
neutrophiles
- Neoplasia de immature
cells (Blasts) >20%
- Subtypes
- ALL (Acute Lymphoblastic
Leukemia)
- Test: TdT+
- Subtypes
- B-ALL
- Causes: t(12,21) NIñOS,
t(9,22) ADULTOS
- Markers: CD10,
CD19, CD20
- Treatment:
Respond well to
chemotherapy,
Need Injection in
scrotum and CSF
- Causes: t(12,21) NIñOS,
t(9,22) ADULTOS
- T-ALL
- Markers:
CD2, CD8
- Characteristics:
MASS
(lymphoma)
- Markers:
CD2, CD8
- B-ALL
- Associated with
Down Syndrome
(AFTER 5 yrs old)
- Test: TdT+
- AML (Acute Myeloblastic
Leukemia)
- Tst: MPO,
Auers Rod
- Subtypes
- Promyelocitic
- Causes: t (15,17)
Retinoic Acid
Receptor
Disrupted, cells
can't mature
- Complications:
Auers Rods
activate
coagulation
cascade, risk for
DIC
- Treatment:
ATRA
- Causes: t (15,17)
Retinoic Acid
Receptor
Disrupted, cells
can't mature
- Monocytic
- Causes:
Neoplastic
proliferation of
Monoblasts
- Characteristics:
Swelling gums
- Causes:
Neoplastic
proliferation of
Monoblasts
- Meakarioblastic
- Lack MPO
- Associated with
Down Syndrome
(BEFORE 5 yrs old)
- Lack MPO
- Promyelocitic
- Myelodisplastic Syndrome
- Characteristics:
HYPERCELLULAR BONE
MARROW (because not
apropiate development of cells)
CITOPENIA (because cells
are stuck in Bone Marrow)
- Blasts <20% but can progress to AML
- Pacientes bajo
quimioterapia o
radioterapia
expuestos a
alkylating agents
- Characteristics:
HYPERCELLULAR BONE
MARROW (because not
apropiate development of cells)
CITOPENIA (because cells
are stuck in Bone Marrow)
- Tst: MPO,
Auers Rod
- ALL (Acute Lymphoblastic
Leukemia)
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