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662926
ISOINMUNIZACIÒN MATERNO FETAL
Description
Mind Map on ISOINMUNIZACIÒN MATERNO FETAL, created by vanessa_1438 on 03/22/2014.
Mind Map by
vanessa_1438
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Created by
vanessa_1438
almost 11 years ago
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Resource summary
ISOINMUNIZACIÒN MATERNO FETAL
Proceso inmunològico iniciado en una mujer RH negativo, con producciòn de anticuerpos, en respuesta al paso de eritrocitos fetales RH positivos
FISIOPATOLOGIA
Exposicion materna a antigenos eritrocitarios
Tipos :
Duffy
RH
Kelly
Kidd
Se produce formación de anticuerpos en contra de esos antigenos
IgG e IgM atraviesan placenta y provocan eritroblastosis fetal
Esto ocasiona anemia e ictericia nenonatal
CAUSAS
Trauma abdominal
Hemorragia feto materna
Embarazo ectópico
CUADRO CLINICO
Anemia hemolítica
Bilirrubina indirecta no mayor a 16mg/100 ml en anemia leve
Ictericia grave del recién nacido
Hepatoesplenomegalia
Hidropesía generalizada
DIAGNÒSTICO
Anamnesis completa dirigida
Estudio completo hemátologico
Ecografía
TRATAMIENTO
En el embarazo
Vigilancia periódica
Alta dosis de gammaglobulina intravenosa inespecifica y plasmaferesis
Transfusión intraútero en casos severeos
Neonatal
Fototerapia
Inmunoglobulina
Exanguinotransfusion
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