Non-Narcotic Analgesics

Description

(DHYG 325- Pharmacology) Mind Map on Non-Narcotic Analgesics, created by fandrickb2 on 05/12/2013.
fandrickb2
Mind Map by fandrickb2, updated more than 1 year ago
fandrickb2
Created by fandrickb2 almost 11 years ago
37
0

Resource summary

Non-Narcotic Analgesics
  1. Salicylates : ASA
    1. inhibits COX1 enzyme, inhibits PG production in response to inflammation
      1. more effective on throbbing pain- inflammation response ex. after an extraction.
      2. mild-moderate pain
        1. reduces fever
          1. antiinflammatory
            1. ANTIPLATELET: irriversible, inhibits thromboxane
              1. used in prophylaxis of MI
        2. DOSE: 325-650mg q4h (pain
          1. 3-6g daily for arthritis
            1. 75-325mg prevention MI
              1. children 10-15mg/kg q4-6hr
              2. ADRs: GI: PG responsible for production of protective mucus in gut & inhibiting gastric acid secretion
                1. Blood clotting: prolongs bleeding 1.5-7 days (depending on dose)
                  1. High doses: tinnitus, Nausa, vomitting. hyperventilation=death soon
                  2. aggrivate ulcers, gastritis, hernia, GERD
                    1. hypersensitivity triad: sensitivity, nasal polyps & athsma
                  3. NSAIDs

                    Attachments:

                    1. Similar to ASA, but more POTENT. reversible platelet aggregation (only as long as its in the blood)
                      1. uses: rheumatoid, gouty & osteoarthritis, fever, dysmenorrhea & assoc. pain
                        1. COX1 present in body at all times, SE assoc w GI, remal function, fluid retention & platelet adhesion
                          1. COX2 present only during trauma, high CV events assoc with COX2 inhibitors, only celebrex/celexicob available
                      2. Acetaminophen
                        1. Equipotent as ASA. Tylonel, Tempra, Panadol. Caffeine usually added
                          1. Provides NO ANTIINFLAMMATORY,
                            1. amtipyretic & analgesic. No effect on CV or resp. syste,.
                            2. Metabolized in liver, avoid use with alcohol or in pts with liver problems
                              1. DOSE: 325-650mg q4-6hr to max of 4g/24hr
                            Show full summary Hide full summary

                            Similar

                            Opioid Analgesics (Narcotics)
                            fandrickb2
                            Asthma Treatment
                            fandrickb2
                            Antiinfective Drugs
                            fandrickb2
                            The Geography Of Earthquakes
                            eimearkelly3
                            MCAT Study Plan
                            Alice McClean
                            TOEFL English Vocab (A - M)
                            Ali Kane
                            A-level Maths: Key Differention Formulae
                            Andrea Leyden
                            All AS Maths Equations/Calculations and Questions
                            natashaaaa
                            GCSE History – Social Impact of the Nazi State in 1945
                            Ben C
                            Language Techniques
                            Anna Wolski
                            1PR101 2.test - Část 19.
                            Nikola Truong