Endometrial Ca

Endometrial Ca

Overview
1. Most common gyne ca.
  1. 30% of all gyne ca
2. 4th cancer in female
3. Present in early stages
4. 5-year survival rate 80%
5. Most common type: Adenocarcinoma
Incidence
1. Life-time risk 1/90
2. Mean age: 54
  1. 25% before menopause
Etiology
1. Exact: unknown, but ass w high estrogen level
2. Risk factors
3. Reduce incidence in
Symptoms
1. 90% Abnormal V Bleeding
  1. PMB
    1. 10% malignancy
  2. Irregular V Bleeding
2. Pre-menopause
  1. IMB
  2. Blood-stained V Discharge
  3. Heavy Mens Bleeding
  4. Lower Abd Pain
  5. Dyspareunia
3. Abnormal cytology on pap smear
  1. Rare!
4. Advanced cases
PE
1. Speculum
  1. Blood from cervical
2. Bimanual
  1. Enlarged uterus
Diagnosis
1. TV US
  1. 4mm
2. Hysteroscopy
3. Biopsy
  1. Pipelle/curettage
  2. Report
    1. Type
    2. Grade
4. MRI
  1. Staging
    1. FIGO
  2. Treatment
Management
1. Surgery
  1. Factors
    1. Grade
    2. Stage
    3. Ptn Comorbidities
  2. Standard
    1. Total hysterectomy + Bilat Salpingectomy
      1. Abdominally
      2. Lap
2. Adjuvant tx
  1. Post-op Radiotx
    1. Recurrence
  2. Chemotx
    1. Mets
Prognosis
1. Adverse factors

Resource summary

	Created by Raihana Nazri almost 11 years ago