SLE Systemic Lupus Erythematosus

Mind Map by LiberatedOrgan, updated more than 1 year ago
Created by LiberatedOrgan almost 6 years ago


First stab at mind mapping. A work in progress.

Resource summary

SLE Systemic Lupus Erythematosus
1 Fatigue
1.1 Fever
1.1.1 Foto-sensitivity
1.2 Flares
1.2.1 Weight Gain H2O, Na+ retention decrease serum albumin
1.2.2 GI issues weight loss
1.3 Classic S/S
1.4 PAIN
2 Vasculitits
2.1 Autoimmune
2.1.1 Chronic inflammation, multiple organs antinuclear antibodies (ANA) target nuclear self antigens Inflammation in an SLE vessel shows activation of complement and inflammatory cell infiltration. Complications r/t increased vascular permeability are systemic, as the name implies, with multiple organs at in increase risk for damage and disease. Serum labs typically show: elevated liver NZs, sed rate, C-reactive protein and creatinine ratio; heyolytic anemia, thrombocytopenia, leukopenia.Outcome of SLE flare: Prevent pancytopenia
2.1.2 abnormal immune function etiology unclear; genetic susceptibility
2.2 pericarditis
2.3 glomerulonephritis / lupus nephritis
2.3.1 hematuria, proteinurea
2.4 keratitis
2.4.1 rash (erythemia) is often first symptom
2.4.2 photosensitive acute cutaneous molar, "butterfly" rash
2.5 Raynaud's Phenomenon
2.5.1 decreased blood flow extremeties vasoconstriction =>cold hands & feet
3 American College of Rheumatology criteria for SLE diagnosis: SOAP BRAIN MD
3.1 S: Serositis
3.2 O: Oral Ulcers
3.3 A: Arthritis
3.4 P: Photosensitivity
3.5 B: Blood disorders
3.6 R: Renal involvement
3.7 A: Antiuclear Antibodies
3.8 I: Immunologic phenomenon
3.9 N: Neurologic disorder
3.10 M: Malar rash
3.11 D: Discoid rash

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