Animal Responses

Description

F215 Mind Map on Animal Responses, created by lauratyley on 27/05/2013.
lauratyley
Mind Map by lauratyley, updated more than 1 year ago
lauratyley
Created by lauratyley almost 11 years ago
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Resource summary

Animal Responses
  1. a) why animals need to respond to their enviroment
    1. survival
      1. avoid harmful envoiroment
        1. respond to changes in there internal enviroment

          Annotations:

          • making sure they are always optimum for enzymes to function
      2. b) the peripheral & central nervous system
        1. periphereal
          1. SENSORY NURONES

            Annotations:

            • carry information from receptor nuerones towards the central nervous system have long cytoplasmic processes that pick up information and transmit action potentials to cell body THEN AXON TO CNS 
            1. CB in DORSAL ROOT GANGLIA
              1. SPINAL NERVE
            2. & MOTOR NURONES

              Annotations:

              • carry infomation from the centeral nervouse system to the effector
              1. CB IN SPINAL CHORD

                Annotations:

                • axons pass out the spinal chord and straight to the effector
                1. VENTERAL ROOT
            3. centeral
              1. brain and spinal chord
                1. spinal cord
                  1. neural arches

                    Annotations:

                    • of the verteabrea. in this nerual arches...
                    1. canal containing cerebro spinal fluid
                      1. mechanical shocks
                        1. provide nutrients and oxygen
                          1. exam q

                            Annotations:

                            • explain why CBF reduces heat of brain, high latent heat of water, cicrulation, absorbs heat
                            1. exam q
                      2. butterfly region in the center

                        Annotations:

                        • contains unmylinated nuerones so appears grey
                        1. surronded by axons and dendrons

                          Annotations:

                          • so they appear white as hey are mainly mylinated 
                        2. brain

                          Annotations:

                          • highly specialised region of the spinal chord
                          1. crainal nerve carry nerves from brain
                          2. both surrounded by meniges

                            Annotations:

                            • 3 membranes that  HELP TO secrete cerebo spinal fluid which fills the spaces inside the brain and he spinal chord
                          3. mostly INTERMEDIATE
                            1. short dendrites forming synapses with many cells
                              1. receive and intergrate information and then pass on AP to other nuerones
                                1. excitory

                                  Annotations:

                                  • causes a depolarisation of the post synaptic membrane the balance between excitory and inhibitory in all the synapses determine whether or not the action potential is passed on down its axon  to another nureone 
                                  1. inhibitory

                                    Annotations:

                                    • inhibtis the depolarisation of the post synaptic membrane
                              2. made of neurones

                                Annotations:

                                • specialised calls that carry eletical impuleses in the form of action potentials around the body, sensory, motor or intermediate
                                1. made of gial cells

                                  Annotations:

                                  • have a variety of functions e.g. help nutrients from the blood pass to neurounes and maintain the balance of ions in the tissue fluid surrounding the brain and spinal chord. Schwann cells are types of Gial Cells 
                                  1. shwann cells
                                2. c) Automoic and Somatic

                                  Annotations:

                                  • the peripheral nervouse system splits into the automic and the peripheral nervouse system
                                  1. automic/Viscera

                                    Annotations:

                                    • self minding not under our voluntary control 
                                    1. All internal organs
                                      1. smooth Muscle
                                        1. walls of artierols
                                          1. walls of the alimentary canal
                                          2. cardiac muscle
                                            1. the exocrine glands

                                              Annotations:

                                              • salivary glands
                                              1. MOTOR
                                                1. MOTOR NUERONES cell body in automic ganglia
                                                  1. PREGANGLIANIC NUERONE

                                                    Annotations:

                                                    • takes infomation from the central nervouse system to the automic ganglia 
                                                    1. out of the venteral root
                                                      1. synapse with motor nuerones
                                                      2. axons leave the AG to synapse with organs/SM
                                                      3. Sympathetic NS
                                                        1. nora adrenaline

                                                          Annotations:

                                                          • is the transmittor substance
                                                          1. stimulate the organs

                                                            Annotations:

                                                            • heart to beat faster with increased pressure, the pupils dilate and the bronchi to dilate
                                                          2. Or Acetycholine
                                                            1. Still stimulatory
                                                              1. sweat glands

                                                                Annotations:

                                                                • sweat glands to produce more sweat and the erector muscles to contract 
                                                                1. erector muscles
                                                                2. flight or flight

                                                                  Annotations:

                                                                  • directly activates target organds
                                                                  1. initatied under stress
                                                                    1. stimulates adrenal glands

                                                                      Annotations:

                                                                      • causes them to secrete adrenaline and noraadrenaline 
                                                                      1. not useful long term

                                                                        Annotations:

                                                                        • flight or fight response can be counter productive in long term situations = negative side ffects on health
                                                                      2. Causes..
                                                                        1. sppeding of HR and BR
                                                                          1. increase in BP
                                                                          2. contraction of radial muscles
                                                                            1. exam q
                                                                              1. Automic ns controls

                                                                                Annotations:

                                                                                • the smooth muscle in the iris
                                                                                1. iris has..

                                                                                  Annotations:

                                                                                  • 2 sets of muscles circular and radial 
                                                                                  1. work antagonistically
                                                                                    1. synpathetic controls..

                                                                                      Annotations:

                                                                                      • radial muscles = pupils open 
                                                                                      1. parasympathetic controls

                                                                                        Annotations:

                                                                                        • the circular muscle = close pupil
                                                                                  2. light hits retina
                                                                                    1. signals from retina to brain

                                                                                      Annotations:

                                                                                      • with regards to how much light is being let in
                                                                                      1. too much light = parasymp

                                                                                        Annotations:

                                                                                        • circular muscles contract this occurs via a reflex action
                                                                                        1. not enough light = symp

                                                                                          Annotations:

                                                                                          • radial muscles contract this occurs via a reflex action
                                                                                  3. relaxstion of sphinchter muscle = urination
                                                                                    1. defecation
                                                                                      1. constriction of arterioles supplying alimentary canal
                                                                                        1. exam q

                                                                                          Annotations:

                                                                                          • describe how internal organs will function differently in a calm mammel compared to a frightened mammel: heat: Calm: rate slow/ small force. Stress: Rate fast and great force.  Lungs: breathing slow/shallow stress: breathing rate fast and deep Muscles: less active / blood flow stress: more active blood flow  Live: Glucose to glycogen glucose taken up Stess: Glycogen - glucose & glucose released  Gut: Peristalsis / secretion / digestion blood flow to gut. streee: les peristalisis / secretions / digestion
                                                                                          1. liver
                                                                                            1. stressed

                                                                                              Annotations:

                                                                                              • glycogen to glucose = glucose is released
                                                                                              1. relaxed

                                                                                                Annotations:

                                                                                                • glucose to glycogen, glucose is taken up
                                                                                              2. lungs
                                                                                                1. stressed

                                                                                                  Annotations:

                                                                                                  • fast breathing rate
                                                                                                  1. relaxed

                                                                                                    Annotations:

                                                                                                    • slow breathing rate
                                                                                                  2. heart
                                                                                                    1. stessed

                                                                                                      Annotations:

                                                                                                      • hr increased and great force
                                                                                                      1. relaxed

                                                                                                        Annotations:

                                                                                                        • hr slow and small force
                                                                                                        1. exam q

                                                                                                          Annotations:

                                                                                                          • what happens when heart during excersise and heart after excersise with reference to the automic nervouse system - during excersise - nerve impulses to cardica accelerator center & impulses to heart via accelerator nerve, ref noradrenaline, impulses to adrenal glands= secrete adrenaline decrease nerve impulses to inhibitor center and from brain to heart via the decelerator nerve, acetycholine, parasympathetic, decrease heart rate 
                                                                                                          1. exam q

                                                                                                            Annotations:

                                                                                                            • if automic nerves cut, heart would still beat  
                                                                                                          2. gut
                                                                                                            1. stressed

                                                                                                              Annotations:

                                                                                                              • no peristalissis, secretions, digestion or blood flow to gut
                                                                                                              1. relaxed

                                                                                                                Annotations:

                                                                                                                • more peristalsis, more digestion, more secretion, blood flow to the gut occouring 
                                                                                                              2. muscle
                                                                                                                1. stressed

                                                                                                                  Annotations:

                                                                                                                  • increase blood flow to muscles 
                                                                                                                  1. relaxed

                                                                                                                    Annotations:

                                                                                                                    • less blood flow to muscles
                                                                                                                  2. stomach

                                                                                                                    Annotations:

                                                                                                                    • gastric juices, involuntary,tast receptors, messages from receptors to cns, automic, acetycholine, parasympathetic and sympathetic, vagus nerve
                                                                                                              3. Parasympatheic NS
                                                                                                                1. rest and digest
                                                                                                                  1. can have stimulatory effect also
                                                                                                                  2. brain, top & base of sc
                                                                                                                    1. cns to effector target organ NO GANGLIA
                                                                                                                      1. many neaurones in vagus nerve

                                                                                                                        Annotations:

                                                                                                                        • the cranial nerve
                                                                                                                        1. carries impulses to thorax and abdomen
                                                                                                                      2. acetycholine
                                                                                                                        1. inhitory effect
                                                                                                                    2. somatic

                                                                                                                      Annotations:

                                                                                                                      • all sensory and motor nuerones from and to the skeletal muscles, involved conscious activities
                                                                                                                      1. skeletal mucles
                                                                                                                        1. MOTOR AND SENSORY
                                                                                                                          1. cns - skeletal muscle
                                                                                                                        2. d) the brain
                                                                                                                          1. Cerebrum

                                                                                                                            Annotations:

                                                                                                                            • largest part of the brain split into two hemisphers, cerable cortex is the largest part, two hemispheres connected by the corpus cullosum. VISION HEARING LEARNING AND THINKING
                                                                                                                            1. cerebal cortex = characteristics that make us human

                                                                                                                              Annotations:

                                                                                                                              • speech, emotion, language , logical though and decision making 
                                                                                                                              1. recieves infomation from all the sense organs

                                                                                                                                Annotations:

                                                                                                                                • such as the eyes and the ears
                                                                                                                                1. Different parts of the body to different sides of the brain

                                                                                                                                  Annotations:

                                                                                                                                  • nerve impulses from the right side of our body go to the left cerebal hemisphere and NI from the left side of our body go to the right hemisphere
                                                                                                                                2. 1. Impulses go to PRIMARY SENSORY AREAS

                                                                                                                                  Annotations:

                                                                                                                                  • 1st recieve nerve impulses from the sense organs 
                                                                                                                                  1. 2. NI then go to ASSOCIATION AREAS

                                                                                                                                    Annotations:

                                                                                                                                    • infomation from the primary sensory areas and other parts of the brain are sent to the association areas and are intergrated together 
                                                                                                                                    1. NI then go to the motor areas

                                                                                                                                      Annotations:

                                                                                                                                      • where nerve impulses are generated and sent to the effectors 
                                                                                                                                      1. Large Assosiation area is Parietal, Temporal and Occipital Lobes
                                                                                                                                        1. where different parts of our body are
                                                                                                                                        2. Association area in frontal lobe
                                                                                                                                          1. Planning actions and movement
                                                                                                                                          2. assosation area = Limbic System

                                                                                                                                            Annotations:

                                                                                                                                            • memory and emotions 
                                                                                                                                            1. Amygdala
                                                                                                                                              1. Coordinates the actions of the automic and the endocrine systems
                                                                                                                                                1. emotions
                                                                                                                                                2. hippocampus
                                                                                                                                                  1. Memeory
                                                                                                                                                3. Association areas in the left
                                                                                                                                                  1. Berocas area
                                                                                                                                                    1. Production of language in speaking and writing
                                                                                                                                                    2. Wernickes area
                                                                                                                                                      1. Understanding language
                                                                                                                                                    3. Right hem
                                                                                                                                                      1. parietal Lobe
                                                                                                                                                        1. visualise objects in 3D and recognise faces
                                                                                                                                              2. Cerebellum
                                                                                                                                                1. folded surface
                                                                                                                                                  1. infomation from stretch receptors in muscles, ears, eyes & other parts of brain
                                                                                                                                                    1. info intergrated to used to coordinate the timing and pattern of skeletal musceles
                                                                                                                                                      1. responsible for balance, coordination, eye movement and fine manipulation
                                                                                                                                                    2. EXAM Q

                                                                                                                                                      Annotations:

                                                                                                                                                      • functions; posture, balance, coordination of skeletal muscles 
                                                                                                                                                    3. Medulla Oblongata
                                                                                                                                                      1. link between the brain and the spinal chord
                                                                                                                                                        1. regulates and controls involuntary movments
                                                                                                                                                          1. breathing
                                                                                                                                                            1. heart rate
                                                                                                                                                              1. exam q

                                                                                                                                                                Annotations:

                                                                                                                                                                • funtions; regulate hr, circulaution, swallowing, breathing rate, bp, peristalisis
                                                                                                                                                            2. Hypothalamus
                                                                                                                                                              1. regulates the autonomic NS
                                                                                                                                                                1. control the secretion of hormones from the pit gland
                                                                                                                                                                  1. effects the controls of many homeostatic processes
                                                                                                                                                                    1. temp reg
                                                                                                                                                                      1. water content in body fluids
                                                                                                                                                                      2. produces hormones
                                                                                                                                                                      3. exam q

                                                                                                                                                                        Annotations:

                                                                                                                                                                        • the hypothalamus constantly monitos and regulates the concentration of hormones in the  blood. outline how the hypothalamus reulates the concentration of hormones in the blood inhibits output of trophic hormones by pituitary gland; which inhibits output of hormones by endocrine glands; blood hormone concentration falls to normal levels; ref. negative feedback; ORA
                                                                                                                                                                      4. exam q

                                                                                                                                                                        Annotations:

                                                                                                                                                                        • alzehimers and the brain: - disrupt cell metabolism -shriveled brain cells - nuerones die slowly  - less brain cells  - shorter/fewer dendrites  -trangels  - enlarged ventricles -plaques -less nuerotransmittor changes: -social skills -language -personality change -inability to learn - memory poor  -difficulty speaking -loss of control of voluntary muscles - anxiety -aggression
                                                                                                                                                                      5. e) Brain & NS co ord muscles
                                                                                                                                                                        1. 1. recieves sensory info
                                                                                                                                                                          1. 2, Decideds on necessary actions
                                                                                                                                                                            1. 3. sends nerve implulses along nuerones to skeletal muscles to C/R
                                                                                                                                                                        2. f) joints and elbows
                                                                                                                                                                          1. muscles

                                                                                                                                                                            Annotations:

                                                                                                                                                                            • specialised tissue that can contract and relax using energy need to respire arerbically to create the energy, when contracts is excerts  force in a particular direction pulling on particular body parts, muscles make sure their behaveouir is coordinated with all the other muscles  muscles are attatched to bones by tendons and ligaments attatch bone to bonea
                                                                                                                                                                            1. elbow

                                                                                                                                                                              Annotations:

                                                                                                                                                                              • catilage lines joints, ligament large circle, synovial membrance  ontop of ligament and synovial fluid fills the space between the joint
                                                                                                                                                                              1. synovial joint

                                                                                                                                                                                Annotations:

                                                                                                                                                                                • adapted to allow smooth movement between two bones, lined with a synoival membrance which secretes synovial fluid which lubricates the joint
                                                                                                                                                                                1. hinge joint

                                                                                                                                                                                  Annotations:

                                                                                                                                                                                  • allowing movement in one plane
                                                                                                                                                                                  1. biceps and triceps

                                                                                                                                                                                    Annotations:

                                                                                                                                                                                    • called this due to the number of tendons that attach them to the humerus and scarpulla 
                                                                                                                                                                                    1. antag

                                                                                                                                                                                      Annotations:

                                                                                                                                                                                      • antagonoistic contraction of one causes the relaxation of another
                                                                                                                                                                                      1. bicep contracts pulls ulna and radius closer to the scapula
                                                                                                                                                                                        1. tricep relax it pulls ulna and radius away from the scapula
                                                                                                                                                                                          1. exam q
                                                                                                                                                                                            1. bicep is...

                                                                                                                                                                                              Annotations:

                                                                                                                                                                                              • flexer muscle = bend arm
                                                                                                                                                                                              1. tricep is a..

                                                                                                                                                                                                Annotations:

                                                                                                                                                                                                • extensior muscle = straighten arm 
                                                                                                                                                                                                1. humerus acts as..

                                                                                                                                                                                                  Annotations:

                                                                                                                                                                                                  • an achor 
                                                                                                                                                                                              2. can act as steadying force

                                                                                                                                                                                                Annotations:

                                                                                                                                                                                                • when one contracts the ther does aswell to make sure a smooth movement
                                                                                                                                                                                            2. exam q

                                                                                                                                                                                              Annotations:

                                                                                                                                                                                              • explain the role of cartilage and synovial fluid: lubrication of the joint, reduce friction, shock absorber, provide nutrients to cartilage cells 
                                                                                                                                                                                          2. g)sliding filment model
                                                                                                                                                                                            1. filaments

                                                                                                                                                                                              Annotations:

                                                                                                                                                                                              • parrele groups of thin filaments lie between groups of thin ones made of protein
                                                                                                                                                                                              1. myofibrils
                                                                                                                                                                                                1. muscle fibres
                                                                                                                                                                                                  1. syncitium

                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                    • many nuclei
                                                                                                                                                                                                    1. sarcolemma

                                                                                                                                                                                                      Annotations:

                                                                                                                                                                                                      • plasma membrane
                                                                                                                                                                                                      1. T tubules

                                                                                                                                                                                                        Annotations:

                                                                                                                                                                                                        • deep infoldings. help spread electircal impulsesthroughout the sarcoplasm so they reach all the muscle fibres  
                                                                                                                                                                                                        1. sarcoplasmic reticulum

                                                                                                                                                                                                          Annotations:

                                                                                                                                                                                                          • internal membrance run through the sarcoplas, they store and release calcium ions thats are needed for muscle contraction 
                                                                                                                                                                                                      2. mito

                                                                                                                                                                                                        Annotations:

                                                                                                                                                                                                        • huge amounts in muscle fibres to produce atp that is needed for muscle contraction
                                                                                                                                                                                                        1. multinucleate

                                                                                                                                                                                                          Annotations:

                                                                                                                                                                                                          • have many nuclei
                                                                                                                                                                                                      3. thick = myosin
                                                                                                                                                                                                        1. A bands
                                                                                                                                                                                                          1. exam q

                                                                                                                                                                                                            Annotations:

                                                                                                                                                                                                            • stays the same during contracting does not shorten
                                                                                                                                                                                                          2. H band = only myosin
                                                                                                                                                                                                            1. exam q

                                                                                                                                                                                                              Annotations:

                                                                                                                                                                                                              • shortens during contraction
                                                                                                                                                                                                            2. bind to m band
                                                                                                                                                                                                              1. head and a tail

                                                                                                                                                                                                                Annotations:

                                                                                                                                                                                                                • tails bind to m line and heads away from m line 
                                                                                                                                                                                                                1. lie in bundels
                                                                                                                                                                                                                  1. hinged
                                                                                                                                                                                                                  2. fiborus
                                                                                                                                                                                                                    1. 2x binding sites on head

                                                                                                                                                                                                                      Annotations:

                                                                                                                                                                                                                      • one for atp and one for actin 
                                                                                                                                                                                                                    2. thin = actin
                                                                                                                                                                                                                      1. I Bands
                                                                                                                                                                                                                        1. exam q

                                                                                                                                                                                                                          Annotations:

                                                                                                                                                                                                                          • shortens during contraction
                                                                                                                                                                                                                        2. bind to z band
                                                                                                                                                                                                                          1. between two z = sacromere
                                                                                                                                                                                                                          2. gobular
                                                                                                                                                                                                                            1. many actin molecules bind = long chain
                                                                                                                                                                                                                              1. two chains twist around = actin filament
                                                                                                                                                                                                                                1. topomyosin and troponin

                                                                                                                                                                                                                                  Annotations:

                                                                                                                                                                                                                                  • also intrevals in filament at regular intervals. troponin is large and looks like sperm, tropomyosin is small and thin like thread
                                                                                                                                                                                                                                  1. tropomyosin blocks binding site for myosin

                                                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                                                    • preventing muscle contraction 
                                                                                                                                                                                                                                  2. one binding site

                                                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                                                    • for myosin called the actin myosin binding site
                                                                                                                                                                                                                              2. contraction

                                                                                                                                                                                                                                Annotations:

                                                                                                                                                                                                                                • triggered by an action potential 
                                                                                                                                                                                                                                1. troponin changes shape causeing the movment of tropomyosin

                                                                                                                                                                                                                                  Annotations:

                                                                                                                                                                                                                                  • change shape because calcium bind to the toponin, action potential triggers the release of calcium from the sarcoplasmic reticulim, troponin chnages shape pulling tropomyosin from binding site on the actin molecule exposing the actin myosin binding site. when relaxed they cover the binding site on actin for myosin preventing contraction
                                                                                                                                                                                                                                  1. myosin head can bind to myosin actin binding site

                                                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                                                    • forming a x bridge between the two filaments called an actin myosin x bridge. release adp and pi - atpase
                                                                                                                                                                                                                                    1. myosin head tilts

                                                                                                                                                                                                                                      Annotations:

                                                                                                                                                                                                                                      • MARK SCHEME; ATP ATTATCHES TO MYOSIN HEAD RESULTING IN THE HYDROLYSIS OF ATP SO THE HEAD TILTS energy used to do this is caused by calcium activating the atpase enzymes which breaks down atp pulling the actin filament along towards the center of the sacromere
                                                                                                                                                                                                                                      1. myosin head hydrolyses atp = energy to force the head to let go of actin

                                                                                                                                                                                                                                        Annotations:

                                                                                                                                                                                                                                        • atp is attatched to myosin head and acts as atpase. atp hydrolysed to break bridge  
                                                                                                                                                                                                                                        1. myosin filament move back but actin does not so myosin head binds to different actin site

                                                                                                                                                                                                                                          Annotations:

                                                                                                                                                                                                                                          • a different actin site further along the filament
                                                                                                                                                                                                                                          1. shortening sacromere
                                                                                                                                                                                                                                  2. relaxatoin

                                                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                                                    • calium ions leave their binding site and are collected back into the endoplasmic reticulum via active transport troponin move back to shape and tropomyosin move block binding site 
                                                                                                                                                                                                                                    1. exam q

                                                                                                                                                                                                                                      Annotations:

                                                                                                                                                                                                                                      • constant muscle contraction can produces toxins, explain why these may be fatal; constant contraction, diffuculty digesting, difficulty breathing due to rib cage contracted
                                                                                                                                                                                                                                  3. h) ATP
                                                                                                                                                                                                                                    1. exam q

                                                                                                                                                                                                                                      Annotations:

                                                                                                                                                                                                                                      • less mitochondria = less respiration, less atp produced for energy, slow metabolism, low body temperature
                                                                                                                                                                                                                                      1. aerobic & ana respiration

                                                                                                                                                                                                                                        Annotations:

                                                                                                                                                                                                                                        • aero: oxidative phos in the mito & atp = creatine   ana: glycolysis but can cause lactate to build up in the muscles in the cytoplasm 
                                                                                                                                                                                                                                        1. small store in muscle

                                                                                                                                                                                                                                          Annotations:

                                                                                                                                                                                                                                          • fibres but this is quickly used up 
                                                                                                                                                                                                                                          1. creatine phosphate/pcr

                                                                                                                                                                                                                                            Annotations:

                                                                                                                                                                                                                                            • stored in their cytoplasm phosphate group can be removed from creatine phosphate molecule and combined with adp = atp and creatine. later when demand slowed down atp used from resipariotion can be combined with creatine = creatine phosphate and adp
                                                                                                                                                                                                                                            1. creatinine in urine

                                                                                                                                                                                                                                              Annotations:

                                                                                                                                                                                                                                              • if no spare atp to regenerate the creatine phosphate 
                                                                                                                                                                                                                                              1. phosphorylate adp
                                                                                                                                                                                                                                                1. stored in cells
                                                                                                                                                                                                                                                  1. anarobic/shorterm

                                                                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                                                                    • does not form lactic acid 
                                                                                                                                                                                                                                                  2. exam q

                                                                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                                                                    • why are mitochondria essential fpr the transmission of impulses across the synaptic cleft; active transport of calcium ions into the synapse, enable movement of vesicles to postsynaptic membrane, exocytosis, atp produces, na and k pump maintain gradient, acetycholine formation
                                                                                                                                                                                                                                                    • why are mito necessary for muscular contraction; atp attatcges to myosin head, hydrolses atp. myosin head tilts = shorten sacromere, atp required for the detatchment of myosin from actin, calcium pump in sacroplasmic reticulum, synthesis of pro
                                                                                                                                                                                                                                                  3. i) synapses and nureomj
                                                                                                                                                                                                                                                    1. neuromuscular juctions

                                                                                                                                                                                                                                                      Annotations:

                                                                                                                                                                                                                                                      • action potential causes uptake of atp, ca2 = vesicles containing acetycholine to fuse to presynaptic membrane, diffuses across syn cleft, bind with receptos on sarcolemma = sodium into the sarcolemma through channels = depolar and action potentials down t tubules calcium channels open in spr bind to troponin and change its shpae moving tropmyosin
                                                                                                                                                                                                                                                      1. acetycholine
                                                                                                                                                                                                                                                        1. exam q

                                                                                                                                                                                                                                                          Annotations:

                                                                                                                                                                                                                                                          • explain how a drug could inhibit acertycholinerase  similar shape, binds to and enters active site, prevents ace entering, competitive
                                                                                                                                                                                                                                                          1. exam q

                                                                                                                                                                                                                                                            Annotations:

                                                                                                                                                                                                                                                            • people with alzheimers disease were treated with a drug that inhibited acetylcholinesterase this improved there short term memory suggest how the drug improves memory prevents ach break down= bind to post membrance and depolarise it and activate the memory circuit
                                                                                                                                                                                                                                                          2. postsym = sarcolemma/muscle
                                                                                                                                                                                                                                                            1. nicotinic cholinergenic receptors
                                                                                                                                                                                                                                                              1. more post synaptic receptors
                                                                                                                                                                                                                                                                1. clefts on memb
                                                                                                                                                                                                                                                                  1. causes..

                                                                                                                                                                                                                                                                    Annotations:

                                                                                                                                                                                                                                                                    • contraction, always 
                                                                                                                                                                                                                                                                    1. ache removes neuro trans
                                                                                                                                                                                                                                                                    2. synapses

                                                                                                                                                                                                                                                                      Annotations:

                                                                                                                                                                                                                                                                      • BOTH: action potential trigger
                                                                                                                                                                                                                                                                      1. variouse n.t
                                                                                                                                                                                                                                                                        1. postsym = other synapse or axon
                                                                                                                                                                                                                                                                          1. variouse receptors
                                                                                                                                                                                                                                                                            1. less postsynaptic receptors
                                                                                                                                                                                                                                                                              1. exam q

                                                                                                                                                                                                                                                                                Annotations:

                                                                                                                                                                                                                                                                                • outline what happens in the membrane of a sensory neurone in response to pressure distortion, sodium gates open sodium ions enter and depolarises receptor potential, threshold, action potentials when reach threshold
                                                                                                                                                                                                                                                                              2. smooth post memb
                                                                                                                                                                                                                                                                                1. causes..

                                                                                                                                                                                                                                                                                  Annotations:

                                                                                                                                                                                                                                                                                  • if an action potential is passed on to the next neurone or not 
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