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12478290
NAFLD
Description
Mind Map on NAFLD, created by mohammed mansour on 25/02/2018.
Mind Map by
mohammed mansour
, updated more than 1 year ago
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Created by
mohammed mansour
about 6 years ago
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Resource summary
NAFLD
Anatomy of the liver
Histology of the liver
Lipid Metabolism
A. Transport of acetyl COA into cytosol B. Carboxylation of acetyl COA C. Assembly of FA chain
Nonalcoholic fatty liver disease (NAFLD) is a condition in which excess fat is stored in the liver with the absence of significant alcohol intake.
Risk factors
Obesity, Diabetes Mellitus, Hypertriglyceridemia, Surgery (Jejunoileal Bypass), Medications (Corticosteroids, Estrogens, Amiodarone), Exposures to organic solvents.
Signs & Symptoms
Elevation of serum transaminases, fatigue, malaise, right upper quadrant discomfort.
Most are asymptomatic
Causes
Metabolic syndrome
defined as having at least two of the following: obesity, insulin resistance, dyslipidemia, and hypertension
Investigation
Waist to hip ratio (WHR)
Physical examination
Complete blood count
Lipid profile
AST and ALT enzymes
X-Ray of abdomen
Complications
cirrhosis, liver failure, liver cancer, edema and ascites, hepatic encephalopathy, hepatorenal syndrome, hepatopulmonary syndrome, hypersplenism, bacterial peritonitis.
Management
Pharmacological
Orlista, Lorcaserin, phentermine-topiramate, Liraglutide.
Bariatric surgery
Affected by
Types of Diets
Atkins Diet
Nutrisystem Diet
Media attachments
Picture8 (binary/octet-stream)
Picture9 (binary/octet-stream)
Picture10 (binary/octet-stream)
Liver Normal (binary/octet-stream)
Picture11 (binary/octet-stream)
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