Skin Ulcers

Description

Mind Map on Skin Ulcers, created by Fatima Alkhateeb on 17/02/2019.
Fatima Alkhateeb
Mind Map by Fatima Alkhateeb, updated more than 1 year ago
Fatima Alkhateeb
Created by Fatima Alkhateeb about 5 years ago
54
0

Resource summary

Skin Ulcers
  1. Histology of the skin
    1. Epidermis
      1. Cells
        1. Keratinocytes
          1. Melanocytes
            1. Langerhan's cells
              1. Merkel cells
              2. Layers
                1. Stratum Basale
                  1. Stratum spinosum
                    1. Stratum granulosum
                      1. Stratum Lucidum
                        1. Stratum Corneum
                          1. Found in thick skin only
                2. Dermis
                  1. Layers
                    1. Papillary
                      1. Reticular
                    2. Hypodermis
                      1. Subcutaneous layer deep to the skin, composed of adipose and areolar connective tissue
                      2. Glands
                        1. Eccrine (sweat glands)
                          1. Apocrine (after puberty)
                            1. Holocrine (sebaceous glands)
                            2. Hair
                              1. Medulla
                                1. Cortex
                                  1. Cuticle
                                2. Skin Functions
                                  1. Protection
                                    1. Sensation
                                      1. Thermo-regulation
                                        1. Secretion
                                        2. Types of skin lesions
                                          1. Macule:Flat lesion with well circumscribed change in color < 1cm
                                            1. Patch : Macule >1cm
                                              1. Papule: Raised solid skin lesion < 1cm
                                                1. Plaque:Papule > 1cm
                                                  1. Vesicle:Small blister containing fluid < 1cm
                                                    1. Bulla:Large blister containing fluid > 1cm
                                                      1. Pustule:Vesicle containing pus
                                                        1. Wheal:Transient smooth papule/plaque
                                                          1. Scale:Scaling off the corneum
                                                            1. Crust:Dry exudate
                                                            2. Dermatological changes
                                                              1. Hyperkeratosis: Increased corneum thickness
                                                                1. Parakeratosis:Retention of nuclei in corneum
                                                                  1. Hypergranulosis: Increased granulosum thickness
                                                                    1. Spongiosis: Transient smooth papule/plaque
                                                                      1. Acantholysis:Separation of epidermal cells
                                                                        1. Acanthosis: Epidermal hyperplasia
                                                                        2. Skin cancer
                                                                          1. Squamous cell carcinoma
                                                                            1. Ulcer with a necrotic base and everted edges, keratin pearls on histopathology
                                                                            2. Basal cell carcinoma
                                                                              1. Rodent ulcer with rolled in edges, basal cells with pallisading pattern
                                                                              2. Melanoma
                                                                                1. significant metastasis, ABCDE's to diagnose it
                                                                              3. Leishmeniasis
                                                                                1. Investigations
                                                                                  1. Amastigotes in tissues using giemsa stain
                                                                                    1. Bone Marrow aspirate test (Sensitivity 54-86%)
                                                                                      1. Splenic aspirate is most sensitive (96-98%)
                                                                                      2. Management
                                                                                        1. Sodium stingluconate
                                                                                          1. Meglumine antimoniate
                                                                                            1. Miltefosine
                                                                                              1. Amphotericin
                                                                                                1. Paromomycin
                                                                                                2. Types
                                                                                                  1. Cutaneous
                                                                                                    1. The lesions typically evolve from papules to nodular plaques to ulcerative lesions, with a raised border and central depression
                                                                                                    2. Visceral
                                                                                                      1. Symptoms range from: severe hepatosplenomegaly, irregular bouts of fever, hyperpigmented granulomatus areas on the skin, weight loss (Kala-Azar)
                                                                                                      2. Mucocutaneous
                                                                                                        1. lesions can lead to partial or total destruction of the mucous membranes of the nose, mouth and throat cavities and surrounding tissues
                                                                                                    Show full summary Hide full summary

                                                                                                    Similar

                                                                                                    Chemistry Equations / Maths
                                                                                                    Georgia B
                                                                                                    CHEMISTRY C1 6
                                                                                                    x_clairey_x
                                                                                                    Macbeth - Charcters
                                                                                                    a.agagon
                                                                                                    Unit 1: Media production & regulation
                                                                                                    c.gale
                                                                                                    Physics equations GCSE
                                                                                                    Mia Jones
                                                                                                    Input Devices
                                                                                                    Jess Peason
                                                                                                    Physics Unit 2 - Force, Acceleration And Terminal Velocity
                                                                                                    Ryan Storey
                                                                                                    AQA AS Biology Unit 2 DNA and Meiosis
                                                                                                    elliedee
                                                                                                    CCNA Security 210-260 IINS - Exam 2
                                                                                                    Mike M
                                                                                                    Aplicaciones TIC
                                                                                                    Klaudyna Filipkowska
                                                                                                    1PR101 2.test - Část 8.
                                                                                                    Nikola Truong