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I always feel fatigued and tired

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Mind Map on I always feel fatigued and tired, created by Alia Rashed on 18/02/2019.
Alia Rashed
Mind Map by Alia Rashed, updated more than 1 year ago
Alia Rashed
Created by Alia Rashed about 5 years ago
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Resource summary

I always feel fatigued and tired
  1. Types of colorectal
    1. Rare
      1. Melanoma
        1. Basal cell carcinoma
        2. Adenocarcinoma
          1. Pathogenesis
            1. Two pathways
              1. MSI
                1. Mutations of mismatch repair envyme
                  1. Accumulation of several Mutation
                2. Adenoma carcinoma sequence
                  1. Mutation of both copies of CPA
                    1. Increased risk for polyp
                      1. K-ras mutation
                        1. Polyp formation
                          1. P53 mutation and increased CO2
                            1. Carcinoma
                  2. Epidemiology
                    2. cloacogenic carcinoma
                      1. squamous cell carcinoma
                        1. Investigations
                          1. CT Scan
                            1. Colonoscopy
                              1. Laboratory Tests
                                1. CBC
                                  1. Tumor markers
                                    1. CEA
                                2. Screening
                                  1. Above 45 and above
                                    1. Relatives with colorectal cancer
                                    2. Risk factors
                                      1. Obesity
                                        1. Diet factor
                                          1. Smoking
                                            1. Age
                                              1. Heriditary polyposis syndromes
                                                1. Male gender
                                                  1. First degree relatives with colon cancer
                                                  2. management
                                                    1. Folfox
                                                      1. 5-flurouracil
                                                        1. Leucoverin
                                                          1. Oxaloplatin
                                                          2. Surgical
                                                            1. Excision of mass
                                                              1. Local
                                                                1. Total
                                                            2. Signs and Symptoms
                                                              1. Unintentional weight loss
                                                                1. Cramping
                                                                  1. change in bowel habit
                                                                    1. Difficulty in receiving oneself
                                                                  2. whysiology of defecation
                                                                    2. anatomy of large intestine

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