CHIKUNGUNYA

vaish_rai28
Mind Map by vaish_rai28, updated more than 1 year ago
vaish_rai28
Created by vaish_rai28 about 5 years ago
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Mind Map on CHIKUNGUNYA, created by vaish_rai28 on 12/15/2014.

Resource summary

CHIKUNGUNYA
1 CAUSATIVE AGENT
1.1 virus : alphavirus from togaviridae family
1.2 vector : Aedes aegyptii mosquito ; no animal reservoir
1.3 Cycle of infection : Man- Mosquito-Man ; Incubation period: 2 to 12 days
2 HISTORY
2.1 First isolated from human patients from Tanzania in 1952
2.2 first appeared in India in 1963
3 SYNONYMS
3.1 CHIK Fever; Buggy creek virus infection; Knuckle fever, Me Trivirus infection, Semliki Forest virus infection
4 SYMPTOMS
4.1 Sudden onset of fever, chills, Lymphadenopathy, Headache, Nausea, Abdominal pain, Joint pain, Low back pain & Rash
5 CLINICAL FEATURES
5.1 Viremia for 5 days; Biphasic fever with remisssion after 6 days; high grade fever; Arthralgia lasting several weeks
6 LAB DIAGNOSIS
6.1 1)Four fold or more rise of HI Antibody 2) IgM capture ELISA using MAbs 3) Indirect Immuno Flourescence Test (I IFT) On infected cells from tissues 4) Virus Isolation – Infant Swiss Albino mice Vero BHK-21 cell lines are used 5) Nucleic acid amplification by PCR & RT PCR
7 TREATMENT
7.1 1)Rest to the patient and mild movements of joints 2)Cold compresses to inflamed joints 3) Liberal fluid intake or IV fluids Analgesics and NSAIDS Paraetamol ± Ibuprofen or aceclofenac or diclofenac Naproxen sodium (Naprasyn, Xenobid) Aspirin should be avoided Hydroxy chloroquine sulphate (HCQS) 200 mg/od Chloroquine phosphate 250 mg/od
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