DNA:

1. DNA
2. RNA
3. Structure
   1. Phosphate
   2. Nitrogenous Bases
      1. Guanine
      2. Adenine
      3. Thymine
      4. Cytocine
   3. 5 Carbon Sugar

Annotations:

• Leading: 5-3 strand Lagging: 3-5 strand

1. Griffith

   Annotations:

   • Fredrick Griffith-   Created an experiment that studied two strains of bacteria that saw the transformation of one to another. 
2. Avery

   Annotations:

   •  Built an experiment based off of Grifith's and identified the macromolicules in the bacteria. He concluded that DNA was releseased 
3. Hershey and Chase

   Annotations:

   • In 1952 Alfred Hershey and Martha Chase published difinitive proof that DNA is the genetic material

Annotations:

• Parental Strands of DNA separate and serve as templates and produce DNA molecules that have one strand of parental DNA and one strand of new DNA

1. Unwinding
   1. Enzyme DNA Helicase

      Annotations:

      • The enzyme DNA helicase unwinds the double helix and breaks the hydrogen bonds
      1. Single Stranded Binding Protiens
         1. RNA Primase

            Annotations:

            • Adds short segments of RNA, called RNA primer to each strand
            1. RNA Primer
2. RNA Polymerase

   Annotations:

   • An enzyme that catalyzes the addition of appropraite nucleotides to new the DNA strand
   1. Okazaki Fragments

      Annotations:

      • The lagging strand is synthesized discontinuously into small segments by the polymerase in the 3'-5' direction