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2454003
Ca Endometrio
Description
Mind Map on Ca Endometrio, created by dr.raul.espinos on 08/04/2015.
Mind Map by
dr.raul.espinos
, updated more than 1 year ago
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Created by
dr.raul.espinos
about 9 years ago
49
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Resource summary
Ca Endometrio
Generalidades
Hemorragia anormal es el signo más común
+ Frecuente x arriba de 50 años
Lesión clásica postmenopausia
Se caracteriza x hiperplasia de endometrio
Factores de riesgo
Propagación
Extensión directa
Diseminación linfatica
Implante
Hematogena
Lesiones precursoras
HIPERPLASIA
endometrial
simple- evoluciona a Ca 1%
compleja 3%
atípica 8%
atípica compleja 29 %
ENARM
Tipos histológicos
Tipo I
"ADENOCARCINOMA ENDOMETROIDE"
80 - 90 %
Hormono dependiente
Buen pronóstico
Mutación PTEN
Lenta evolución
Tx QX elección
Tipo II
Carcinoma tipo seroso y cel. clara
+ Frecuiente en menopausia
Evolución más agresiva
Mal pronóstico
HER2/neu P53 Presentes
Tx QT
Cuadro Clínico
Utero aumentado
Hemorragia vaginal 80%
Poscoital
Metorragia
"Agua de lavar carne"
Hematometra
Sangre en utero x estenosis cervical
Piometra
Infiltrado del sangradoen cavidad uterina
Colico abdominal
Dx
1º USG
Endovaginal
Grosor endometrio
Premenopausia
> 12 mm = Hiper
Indicación de biposia
Posmenopausia
> 5 mm = Hiper
Tx
Lavado peritoneal
Histerectomía total con salpingooforectomia bilateral
Tx de hiperplasia endometrail
Progesterona o Histerectomía
Media attachments
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