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2634016
Insulin resistance/ Metabolic syndrome
Description
Mind map of insulin resistance
Mind Map by
rebeccasteele96
, updated more than 1 year ago
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Created by
rebeccasteele96
almost 9 years ago
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Resource summary
Insulin resistance/ Metabolic syndrome
dysregulation of insulin & glucose metabolism
Symptoms
hyperkeratosis skin conditions
type 2 diabetes
High blood pressuer
acne vulgaris
Causes
refined CHO
Increased Blood Sugar
GL = GI of food x CHO per serving
Higher GL= Higher Blood sugar=higher release of insulin
HEALTHY person= rapid uptake of glucose in peripheral cells (blood cells)
GI measure rise in blood sugar after eatinga specific food.
reduce blood sugar
add protein
Lower GL Foods
reduction in sensitivity of insulin receptors - hyperinsulinaemia
lack of exercise
insulin receptor resistance
TYPE 1 -insulin deficiency
Decrease in sensitivity of body tissues to the action of insulin
chronic elevation of blood glucose
Insulin
VLDL
Free fatty acids - inhibit insulin uptake
Dyslipidaemia
glucgon activates hormone sensitive lipase - stimulates Free fatty acids into blood stream
the liver - glucagon stimulates triglycerides synthesis - so cholestorol, shifts from HDL to VLDL
biochemical changes
pancreatic beta cell release more insulin
resistant tissue
adipose
Liver
Skeletal muscle
< in glucose in muscle cells, increases conversion of amino acids, = >glucose. ^alamine levels & pancreatic cells produce glucogen - action on liver cells stimulating glycolysis &glucogenesis >more glucose released
TYPE 2 DIABETEs
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