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Sickle Cell Anemia

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(Biology Exam 2) Mind Map on Sickle Cell Anemia, created by izzy5605 on 22/10/2013.
izzy5605
Mind Map by izzy5605, updated more than 1 year ago
izzy5605
Created by izzy5605 about 13 years ago
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Resource summary

Sickle Cell Anemia
  1. change in one nucleotide
    1. changes entire amino acid sequence
      1. changes structure of protein
        1. changes shape of red blood cell (sickle shape)
          1. protein misfolding
            1. some hydrophobic amino acids could be displayed on surface
              1. changes cell function
      2. inherited
        1. protein aggregation
          1. because of misfolding they clump together
          2. malaria
            1. one sickle cell mutation and one non mutated gene
              1. resistant to malaria
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