Mutations

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Homework of Biology Mind map Mutations.
JOSE MADRID
Mind Map by JOSE MADRID, updated more than 1 year ago
JOSE MADRID
Created by JOSE MADRID almost 5 years ago
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Mutations
  1. Chromosomal Mutations
    1. A mutation involving a long segment of DNA. These mutations can involve deletions, insertions, or inversions of sections of DNA. In some cases, deleted sections may attach to other chromosomes, disrupting both the chromosomes that loses the DNA and the one that gains it. Also referred to as a chromosomal rearrangement.
    2. Gene Mutations
      1. Frameshift Mutation
        1. A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three. "Divisible by three" is important because the cell reads a gene in groups of three bases. Each group of three bases corresponds to one of 20 different amino acids used to build a protein. If a mutation disrupts this reading frame, then the entire DNA sequence following the mutation will be read incorrectly.
        2. Point Mutation
          1. A point mutation is when a single base pair is altered. Point mutations can have one of three effects. First, the base substitution can be a silent mutation where the altered codon corresponds to the same amino acid. Second, the base substitution can be a missense mutation where the altered codon corresponds to a different amino acid. Or third, the base substitution can be a nonsense mutation where the altered codon corresponds to a stop signal.
        3. Factors that cause Mutations
          1. Replication Errors
            1. Examples
              1. Mutations, DNA polymerase proofreading, Mismatch Repair, etc.
            2. Mutagens
              1. Examples
                1. Radioactive substances, x-rays, ultraviolet radiation, heat and radiation.
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