Opioid Analgesics (Narcotics)

fandrickb2
Mind Map by , created almost 6 years ago

(DHYG 325- Pharmacology) Mind Map on Opioid Analgesics (Narcotics), created by fandrickb2 on 12/05/2013.

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fandrickb2
Created by fandrickb2 almost 6 years ago
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Opioid Analgesics (Narcotics)
1 Central Acting, strong analgesia,

Attachments:

1.1 MOA: affects the response to pain by depressing the reaction

Attachments:

2 ADRs
2.1 resp. depression, nausea, vomitting, constipation, urinary retention, anxiety, dysphoria, dec.HR/BP (stimulate vagus nerve)
2.2 Addiction Tx: methadone, long acting agonist, cold turkey
2.3 Overdose: opioid antagonist- naltrexone reverses opioid induced respiratory depression
3 Classification: structure, receptor or strength
3.1 Strength
3.1.1 Strong: morphine, methadone, meperidine, hydromorphone
3.1.1.1 Moderate: oxycodone,pentazocine,
3.1.1.1.1 weak: hydrocodone, codeniene, propoxyphene
3.1.1.1.1.1 Natural: enkephalins, endorphins & dynorphins
3.2 Receptors
3.2.1 Mu agonists: most common
3.2.2 kappa receptor agonist/mu receptor antagonists
3.2.3 mu receptor antagonists: overdose
3.3 Structure
3.3.1 morphine & Codiene
3.3.2 Methadone: blocks the high
3.3.3 morphinan: kappa receptors
3.3.4 meperidine

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