The link reaction

lucy.wright73
Mind Map by , created over 5 years ago

A Levels Biology A2 revision Mind Map on The link reaction, created by lucy.wright73 on 01/29/2014.

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lucy.wright73
Created by lucy.wright73 over 5 years ago
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The link reaction
1 Converts pyruvate (from glycolysis) to acetate. NAD is reduced.
1.1 Decarboxylation and dehydrogenation are enzyme catalysed reactions (pyruvate is substrate)
1.1.1 Pyruvate dehydrogenase removes H atoms; pyruvate decarboxylase removes a carboxyl group
1.1.2 Coenzyme NAD accepts the H atoms; coenzyme A (CoA) accepts the acetate > acetyl CoA
2 Takes place in the matrix, so pyruvate has to be transported into mitochondria from the cytoplasm
3 2 pyruvate + 2 NAD+ (oxidised) + 2 CoA ------> 2 CO2 + 2 reduced NAD + 2 acetyl CoA
3.1 No ATP produced, but each NADH carrying 2 H atoms - will take to inner mitochondrial membrane where H atoms used to produce ATP during oxidative phosphorylation
3.2 2 molecules of everything because two molecules of pyruvate derived from each glucose molecule
4 Pyruvate is 3C, acetate is 2C, acetyl CoA is 2C

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