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E.coli

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Mind Map on E.coli, created by sam.hilton on 04/05/2013.
sam.hilton
Mind Map by sam.hilton, updated more than 1 year ago
sam.hilton
Created by sam.hilton about 11 years ago
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Resource summary

E.coli
  1. Pathogenic types
    1. Enteropathogenic
      1. Destroys microvilli
        1. Loss of tight junctions
        2. Attaching and effacing lesions
          1. Intimin/Tir interaction
            1. TypeIII SS
              1. EspA, B and D
              2. Effect on host signalling
                1. EHEC
                  1. Espfu>N-WASP>Arp2/3
                  2. EPEC
                    1. Nck>N-WASP>Arp2/3
              3. Enterohaemorrhagic
                1. Verocytotoxin producing
                  1. Shigatoxin producing
                    1. Stxb
                      1. Gb3 mediated entry
                      2. Stxa
                        1. Cleaves 28S rRNA
                      4. Enterotoxigenic
                        1. Toxins
                          1. LT
                            1. ADP ribosylation Gsalpha
                              1. CFTR phosphorylated
                            2. ST
                              1. STa
                                1. Guanylate cyclase C
                                2. STb
                                  1. Sulphatide
                              2. Adherence
                                1. CFs and TibA/Tia
                              3. Enteroinvasive
                                1. Endocytic route
                                  1. Intracellular survival
                                2. Enteroaggregative
                                  1. Biofilm
                                    1. AAF1
                                    2. Toxins
                                      1. EAST
                                    3. Diffusely adherent
                                      1. Finger projections
                                        1. Dr/DAF
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