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9121216
Anemia: ↓ or Ineffective RBC production
Description
Mind Map on Anemia: ↓ or Ineffective RBC production, created by Sarah Phillips on 28/05/2017.
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Mind Map by
Sarah Phillips
, updated more than 1 year ago
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Created by
Sarah Phillips
almost 7 years ago
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Resource summary
Anemia: ↓ or Ineffective RBC production
Hematopoetic Stem Cell Failure/BM failure
Acquired/Hereditary Aplastic Anemia
N RDW, ↑ MCV
Fanconi's Anemia
Diamond-Blackfan Anemia
Functional Impairment of Erythroid Progenitors
Abn DNA sythesis: megaloblastic anemia
↑ RDW, ↑MCV
Asynchronous RBC maturation
↓ Folate, B12, IF
lack of functional IF = pernicious anemia
MDS & erythroleukemia
↑ RDW, ↓ MCV, ↓ HGB, ↓ retic
IDA
defective heme synthesis
most common anemia
Thalassemia
Quantitative ↓ Hgb abn
alpha and beta chain gene deletions
Anemia of Chronic Dx & Inflammation
Fe present but not available
Most common hospital anemia
Sideroblastic Anemia
Acquired, Inherited
Non heme iron trapped in mitochondria
iron can't be used to make heme
Abn Hgb synthesis
N or ↓ retic
Chronic Renal Dx
↓ EPO
BM can't ↑ RBCs to compensate for tissue hypoxia
N MCV
Uremia, burr cells
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