Flashcards
Neuronal Communications I
Flashcards do conjunto (18)
- 1Purpose of chemical synapsesPrevent direct electrical propagation of AP from pre to post-synaptic neuron
- 2Synaptic delay~0.5ms
- 3MOA1. AP reaches terminal
2. Membrane depol
3. Opens voltage-gated Ca++ channels
4. Incoming Ca++ causes vesicles containing neurot to fuse with membrane of pre-synaptic terminal.
5. Neurot released into s. cleft
6. Neurot goes to post-r
7. At end neuro removed from C.cleft - 4Kiss-and-run theoryVesicle docks on pre-synaptic membrane
Opens pore
Releases content into cleft and is recycled w/in pre to be used again - 5Removal methodsGlial cell re-uptake
Enzyme degradation
Pre-S active re-uptake - 6How is Noradrenaline removed?Uptake mech involving
Monoamine oxidase
Catechol-o-methyl transferase - 7What is a downward/upward deflecting of RMP?Downward = increase in potential (more polar)
Upward = decrease in potential (less polar) - 8In what quantity is Ach released onto skeletal muscle?In excess to ensure sufficient EPSP for AP
- 9IPSP actionPre-S releases neurot that opens Cl- in or K+ out channels to hyperpolarise the cell
- 10What is convergence?Several neurons relaying signals to a single neuron
- 11What is divergence?One neuron releasing neurot onto multiple neurons
- 12What is typical morphologically of a neuron that needs to integrate many sensory signals?Lots of dendrites
- 13What if it needs to control many outputs?Many axons
- 14Diagram of temporal summationEX1EX1
Short delay - 15Spatial summationEX1 EX2
EX1EX2 - 16EPSP-IPSP cancellationEX1 IN1
- 17Temporal summation occurs becauseFast frequency stimulation of excitatory-presynaptic inputs is additive and causes fusion of vesicles resulting in more quanta released, a larger depolarisation and increased likelihood of threshold being reached
- 18Spatial SummationAccumulation of multiple excitatory pre-synaptic inputs leading to threshold being reached
Informações
- Descrição
- FlashCards sobre Neuronal Communications I, criado por J yadonknow em 28-05-2018.
- Criado por
- J yadonknow
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