Immune Response

Immune Response

Adaptive Immune Response

APC

Helper T cells

Memory T cells

Cytotoxic T cells

- Cancerous cells

- Virus infected cells

Cell-mediated immunity

Kill

Memorise

MHC

B cells

Plasma cells

Memory B cells

Antibodies

Form immune complex

Memorise

Aintibody- mediated immunity

Innate Immune Response

Physical and chemical barriers

Skin - produces antimicrobial fatty, inhibits pathogen colonization

Stomach acidity - Inhibits microbial growth

Inflammatory Response

Damaged cells release histamine, cause capillaries to dilate and become more permeable

Enlarged capillaries cause skin to redden

Swelling stimulates free nerve endings, causing pain

Neutrophils and monocytes migrate to the site of injury

Acute-phase protein is released, make it easier for phagocytocist.

Phagocytes, NK and protein

Natural Killer cells

Cell-to-cell contact

Cells that lack MHC-1 may be recognized and killed

Phagocytes

Neutrophills - Release antimicrobial peptides and bacteria-digesting enzymes

Eosinophils - Mount an attack against parasites

Macrophages and dendritic cells - Engulf and destroy pathogens

Protein

Complement :

- Enhanced inflammation

- Bind to pathogens coated antibodies

- Form a membrane attack complex that produces hole

Interferon :

- Bind to receptors of non-infected cells

- Cuses them to produce substances that interfere with viral replication