Molar pregnancy/ hydatidiform mole

Descrição

Mapa Mental sobre Molar pregnancy/ hydatidiform mole, criado por Zulhilmi Zainal em 20-05-2014.
Zulhilmi Zainal
Mapa Mental por Zulhilmi Zainal, atualizado more than 1 year ago
Zulhilmi Zainal
Criado por Zulhilmi Zainal aproximadamente 10 anos atrás
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Resumo de Recurso

Molar pregnancy/ hydatidiform mole
  1. an egg that is missing its nucleus is fertilized and that may or may not contain fetal tissue
    1. complete moles
      1. single (90%) or two (10%) sperm combining with an egg which has lost its DNA (the sperm then reduplicates forming a "complete" 46 chromosome set
        1. higher risk of developing into choriocarcinoma
          1. all the chorionic villi are vesicular, and no sign of embryonic or fetal development is present
          2. partial mole
            1. an egg is fertilized by two sperm or by one sperm which reduplicates itself yielding the genotypes of 69,XXY (triploid) or 92,XXXY (tetraploid)
              1. fetus is always malformed and is never viable
            2. spontaneous abortion if untreated
              1. Clinical presentation
                1. painless vaginal bleeding in the fourth to fifth month of pregnancy
                  1. uterus may be larger than expected, or the ovaries may be enlarged
                    1. hyperemesis
                      1. very high levels of human chorionic gonadotropin (hCG)
                        1. "cluster of grapes" or "honeycombed uterus" or "snow-storm"
                          1. increased trophoblast proliferation and enlarging of the chorionic villi
                            1. sonogram & histopathological examination
                            2. Treatment
                              1. surgical curettage
                                1. avoid the risks of choriocarcinoma
                                2. avoid pregnancy for at least 6 to 12 months

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