Flashcards
Aspirin
Flashcards do conjunto (15)
- 1Trade namesAspro, Disprin, Solprin, Astrix
- 2Chemical nameAcetylsalicylic acid
- 3Therapeutic classNSAID/antipyretic
- 4Pharmaceutical classSalicylates
- 5IndicationsInflammatory conditions: osteoarthritis, rheumatoid arthritis
Fever
Mild - Mod pain
Prophylaxis of transient ischaemic attacks and MI - 6ActionProduces analgesia and reduces inflammation by inhibiting the production of prostaglandins
Also decreases platelet aggregation - 7Therapeutic effectsAnalgesia, reduction of inflammation and fever, decrease in transient ischaemic attacks and MI
- 8Pharmacokinetics (absorption)Well absorbed from the upper small intestine. Enteric (SR) absorption may be unreliable. Rectal absorption is slow & variable.
- 9Pharmacokinetics (Distribution)Rapidly & widely distributed, crossing the placenta and entering the breast milk
- 10Pharmacokinetics (metabolism & excretion)Extensively metabolised by the liver, inactive metabolites excreted by the kidneys
- 11Pharmacokinetics (half-life)2 -3 hours for low doses, 15 - 30 hours for high doses where the liver reaches saturation
- 12Contraindications/precautionHypersensitivity to aspirin or other salicylates
Bleeding disorders or thrombocytopenia (low platelet count)
History of GI bleeding or ulcer disease
History of asthma - 13Adverse reactions or side effectsENT: tinnitus, GIT: bleeding, dyspepsia, N + V, epigastric distress, abdo pain. HEP: hepatotoxicity HAEM: anemia, hemolysis SKIN: rash, urticaria
- 14AssessmentPain & fever
Lab tests: monitor hepatic function if signs of hepatotoxicity occur or if long term therapy is undertaken - 15EducationAdvise patient to report: tinnitus, unusual bleeding or bruising, black tarry stools or fever > 3 days
Informações
- Descrição
- Need to know for HPA exam
- Criado por
- Usuário eliminado · jun 2018
- Atualizado
- 3 jun 2018
- Visualizações
- 13
- Histórico
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- Criado por Em J · 3 jun 2018
- Copiado por Em J · 3 jun 2018
- Avaliação