Quiz
ON11 Leukemia & Lymphoma
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Perguntas do quiz (15)
1Leukemias - cancer of the body's blood-forming tissues:
Acute Myeloid Leukemia
Chronic Myeloid Leukemia
Acute Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
Note: Acute leukemia involves the immature cells, called [blank_start]stem[blank_end] cells, whereas chronic leukemia develops in [blank_start]mature[blank_end] cells. Myeloid = bone marrow and [blank_start]RBCS[blank_end], lymphocytic = [blank_start]WBCs[blank_end].
Lymphomas(cancer beginning in lymphocytes)
- Non-Hodgkin’s Lymphoma
More [blank_start]common[blank_end], more likely to be in older patients. Begins in [blank_start]any[blank_end] nodes.
- Hodgkin’s Lymphoma
Hodgkin's lymphoma is marked by the presence of [blank_start]Reed-Sternberg[blank_end] cells, which a physician can identify using a microscope. In Non-Hodgkin lymphoma, these cells are not present. Typically begins in the [blank_start]upper[blank_end] body, such as the neck, chest or armpits.- Astem
- Bmature
- CRBCS
- DWBCs
- Ecommon
- Fany
- GReed-Sternberg
- Hupper
2Choose the incorrect epidemiology statement.
- ABlood cancers combined are the 5th most common cancer in NZ
- BLymphoma most common in 35-50 year olds
- CLeukemia most common childhood cancer
- D21,000 people living with blood cancers in NZ
- ABlood cancers combined are the 5th most common cancer in NZ
3Which of these is not a risk factor for leukemia?
- APrevious cancer treatment
- BGenetic disorders
- CExposure to certain chemicals
- DSmoking
- EFamily history
- FYoung
4Select ALL the risk factors for NON-Hodgkin's lymphoma.
- APrevious infection with EBV
- BWeak immune system
- CFamily history
- DChemical exposures
- EPrevious chemo or radiation
- FImmune deficiency / HIV
5There are no widely recommended screening tests for leukemias and lymphomas but they may be identified through routine bloodwork.
- AVerdadeiro
- BFalso
6Clinical Presentation:
Coughing / [blank_start]chest[blank_end] pain
Fever / chills
Frequent [blank_start]infections[blank_end]
[blank_start]Itchy[blank_end] skin or rash
Loss of [blank_start]appetite[blank_end] or nausea
[blank_start]Night[blank_end] sweats
Persistent [blank_start]weakness[blank_end] and fatigue
Shortness of [blank_start]breath[blank_end]
[blank_start]Swollen[blank_end], painless lymph nodes in neck, armpits, or groin - Achest
- Binfections
- CItchy
- Dappetite
- ENight
- Fweakness
- Gbreath
- HSwollen
7Leukemia diagnosis:
- Signs and symptoms
- Complete [blank_start]blood cell count[blank_end]
- [blank_start]Bone marrow[blank_end] biopsy
Lymphoma diagnosis:
- Signs and symptoms
- [blank_start]Lymph Node[blank_end] biopsy/extraction
- Complete blood cell count
- Bone marrow biopsy
- [blank_start]Imaging[blank_end] (look for signs in other parts of your body)- Ablood cell count
- BBone marrow
- CLymph Node
- DImaging
8Prognosis:
Leukemia -
Children (ALL) - [blank_start]90[blank_end]% cured
Adults (ALL) - [blank_start]80-90[blank_end]% achieve remission
Adults (AML) - [blank_start]60-70[blank_end]% achieve remission
+ 70% 5-year survival ALL.
Lymphoma:
HL - 5-year survival [blank_start]86%[blank_end]
NHL:
Localized - [blank_start]72%[blank_end]
Regional - 72%
Distant - [blank_start]55%[blank_end]- A90
- B80-90
- C60-70
- D86%
- E72%
- F55%
9Treatment – Acute Lymphocytic Leukemia.
1. Induction of remission - [[blank_start]vincristine, steroid, anthracycline[blank_end], +/- [blank_start]imatinib[blank_end]] = 1-2 months
2. Consolidation (intensification) [same drugs, high doses] = [blank_start]2-4[blank_end] months
3. Maintenance [[blank_start]methotrexate, 6MP[blank_end], +/- imatinib] = 2 [blank_start]years[blank_end]
CNS treatment/prophylaxis (may be continued through all phases):
Intrathecal [methotrexate]
High dose [blank_start]IV[blank_end] methotrexate
[blank_start]Radiation[blank_end]- Avincristine, steroid, anthracycline
- Bimatinib
- C2-4
- Dmethotrexate, 6MP
- Eyears
- FRadiation
- GIV
10Treatment – Chronic Lymphocytic Leukemia:
Watch and [blank_start]wait[blank_end]
Once symptoms appear / disease progressing: Many different combinations of standard [blank_start]chemotherapy[blank_end] used, in addition to [blank_start]targeted[blank_end] therapy, and/or monoclonal antibodies [[blank_start]rituximab, imatinib[blank_end]].
HSCT (Stem Cell Transplants) a possibility for high risk patients.- Await
- Bchemotherapy
- Ctargeted
- Drituximab, imatinib
11Treatment – Non-Hodgkin’s Lymphoma
Chemotherapy – [blank_start]6-8[blank_end] cycles of combination therapy over several months:
- [blank_start]CHOP[blank_end] [Cyclophosphamide, Doxorubicin, Vincristine, Prednisone]
- R-CHOP [add [blank_start]Rituximab[blank_end] if CD20 positive]
- [blank_start]CVP[blank_end] [Cyclophosphamide, Vincristine, Prednisone]
- [blank_start]ICE[blank_end] [Ifostamide, Carboplatin, Etoposide]
Radiation and HSCT are also options for high risk patients .- A6-8
- BCHOP
- CRituximab
- DCVP
- EICE
12Select all drugs in the CHOP chemo combo.
- ACyclophosphamide
- BDoxorubicin
- CDocetaxel
- DVincristine
- EPrednisone
- FCisplatin
13Monitoring intrathecal CT:
- Every [blank_start]dose[blank_end], check symptoms - Headache, [blank_start]visual[blank_end] changes, fatigue, [blank_start]balance[blank_end] issues, soreness/[blank_start]bruise[blank_end] at entry?
- [blank_start]Weekly[blank_end] labs for blood cell [blank_start]count[blank_end]
- Check for signs of infection [blank_start]daily[blank_end]- Adose
- Bvisual
- Cbalance
- Dbruise
- EWeekly
- Fcount
- Gdaily
14What are the signs/symptoms of Febrile Neutropenia?
- AFever (>38.3 C or > 38.0 C over 1 hour) and ANC <500 cells/mm^3
- BFatigue/weakness ANC <500 cells/mm^3
- CFever (>38.3 C or > 38.0 C over 1 hour) and ANC <300 cells/mm^3
- DFatigue/weakness ANC <300 cells/mm^3
15Watch and wait is an appropriate strategy for which type of blood cancer?
- AHodgkin’s Lymphoma
- BChronic Lymphocytic Leukemia
- CAcute Myeloid Leukemia
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- O usuário eliminou as informações de disciplina Quiz sobre ON11 Leukemia & Lymphoma, criado por Usuário eliminado em 09-10-2019.
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- Criado em 9 out 2019 · atualizado em 9 out 2019
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