Germinal Centres

Affinity Maturation- Dark Zone

Affinity Maturation- Centroblasts

Affinity Maturation- Somatic Hypermutation

Affinity Maturation- Follicular Dendritic Cells's

Follicular DCs- Catch & Hold

Follicular DCs- Ag's

Follicular DCs- Reduced Affinity BCRs

Follicular DCs- Increased Affinity BCRs

Follicular DC Iccosomes- Release

Follicular DC Iccosomes- Uptake by B cells

Follicular DC Iccosomes- T-Cell Binding

Follicular DC Iccosomes- Cytokines

B Cell Proliferation/Class Switching