FINAL REVIEW

Question

Which of the following is NOT indicative of accelerated red cell destruction?

Answer 1

decreased RBC, Hgb, Hct

Answer 2

increased unconjugated bilirubin, increased LDH

Answer 3

increase hemopexin

Answer 4

erythoid hyperplasia

Answer 5

URINE: increased urobilinogen, free hemoglobin, methemoglobin, hemosiderin

Answer 6

increased retics

Answer 7

spherocytes/schistocytes

Answer 8

increased unconjugated bilirubin

Answer 9

decreased poikilocytosis

Answer 10

A, B, and C

Answer 11

All of the above.

Answer 12

significant increase in LDH

Answer 13

hemoglobinemia

Answer 14

hemosiderinuria

Answer 15

IgG antibodies

Answer 16

decreased hemopexin

Answer 17

spherocytes

Answer 18

IgG antibodies

Answer 19

presence of gall stones

Answer 20

splenomegaly

Answer 21

spherocytes

Answer 22

EDTA-borate buffer and cellulose acetate gel

Answer 23

enzymatic reactions that move from cathode to anode

Answer 24

able to separate HbC from HbE

Answer 25

HbA2 ion exchange chromatography

Answer 26

HPLC: High Performance Liquid Chromatography

Answer 27

IEF: Isoelectric Focusing

Answer 28

Capillary Electrophoresis

Answer 29

Globin Chain Electrophoresis

Answer 30

All of the above

Answer 31

Ion Exchange Chromatography

Answer 32

Globin Chain Electrophoresis

Answer 33

Isoelectric Focusing

Answer 34

Gas Chromatogrpahy

Answer 35

Ion Exchange Chromatography

Answer 36

Capillary Electrophoresis

Answer 37

Gel Electrophoresis

Answer 38

Beta-Thal Major

Answer 39

Alpha-Thal Minor

Answer 40

Beta-Thal Minor

Answer 41

Megaloblastic Anemia

Answer 42

Hereditary Persistence of Fetal Hemoglobin (HPFH)

Answer 43

Paroxymal Nocturnal Hemoglobinuria (PNH)

Answer 44

Autoimmune Hemolytic Anemia (AIHA)

Answer 45

Filariasis

Answer 46

acidified serum

Answer 47

neutral serum

Answer 48

alkaline serum

Answer 49

persistant fluorescence

Answer 50

weak or no fluorescence

Answer 51

NADPH not produced

Answer 52

NAD produced

Answer 53

Gram stain

Answer 54

Wright stain

Answer 55

Supravital stain

Answer 56

Eosin stain

Answer 57

Vascular System

Answer 58

Platelet Activity

Answer 59

Coagulation System

Answer 60

Fibrinolytic System

Answer 61

Thrombin System

Answer 62

Regulatory System

Answer 63

VonWillebrande's Factor

Answer 64

Thromboplastin

Answer 65

Tissue Plasmimnogen Factor Inhibitor

Answer 66

Phospholipid

Answer 67

Negatively Charged Surface

Answer 68

produced by platelets

Answer 69

causes vasoconstriction

Answer 70

induces aggregation

Answer 71

inhibited by aspirin

Answer 72

all of the above are true

Answer 73

GPIIb/IIIa

Answer 74

Collagen binding site

Answer 75

Bernard-Soulier Syndrome

Answer 76

von Willebrande Disease

Answer 77

Gray Platelet Syndrome

Answer 78

Glanzmann's Thrombasthenia

Answer 79

Hemophilia A

Answer 80

Glanzmann's Thrombasthenia

Answer 81

Grey Platelet Syndrome

Answer 82

Storage Pool Disease

Answer 83

Glanzmann's Thrombasthenia

Answer 84

Gray Platelet Syndrome

Answer 85

Storage Pool Disease

Answer 86

Tissue factor

Answer 87

Phospholipid

Answer 88

FXI activation

Answer 89

FVIII activation

Answer 90

FXIII activation

Answer 91

Fibrinogen --> Fibrin

Answer 92

FVII activation

Answer 93

both VIII:C and VIII:Ag are deficient in hemophilia

Answer 94

FVIII is released from vWF by prothrombin

Answer 95

FVIII is labile and degrades rapidly when unbound from vWF

Answer 96

FVIII is synthesized in the liver

Answer 97

endothelial cells

Answer 98

plasma cells

Answer 99

bone marrow

Answer 100

Prolonged PT

Answer 101

Normal aPTT

Answer 102

Prolonged aPTT

Answer 103

Prolonged TT

Answer 104

Hemophilia A (FVIII Deficiency)

Answer 105

Hemophilia B (FIX Deficiency)

Answer 106

Hemophilia C (FXI Deficiency)

Answer 107

activated by thrombin generation by binging to thrombomodulin on endothelial cells

Answer 108

inactivates activated V and VIII

Answer 109

main regulatory system

Answer 110

plasminogen converted Protein C to APC

Answer 111

Prevent thrombi from getting too large

Answer 112

Aids in wound healing

Answer 113

Prevents thrombosis in undesirable places

Answer 114

All of the above

Answer 115

None of the above

Answer 116

alpha-2 antiplasmin

Answer 117

Plasminogen activator inhibitor-1 (PAI-1)

Answer 118

Tissue Plasminogen Activator

Answer 119

Thrombomodulin

Answer 120

Hypersplenism

Answer 121

Post-splenectomy

Answer 122

Acute Blood Loss

Answer 123

Proliferation of stem cells

Answer 124

Formation of a blood clot following an injury to a blood vessel

Answer 125

Formation of a blood clot inside an intact blood vessel, obstructing the flow of blood

Answer 126

Formation of a blood clot that is easily solubilized

Answer 127

A portion of a larger clot that breaks free

Answer 128

Protein C deficiency

Answer 129

Factor Deficiency

Answer 130

Hemophilia A or B

Answer 131

thrombi in arm

Answer 132

thrombi in abdomen

Answer 133

thrombi in deep leg

Answer 134

thrombi in kidney

Answer 135

Pulmonary artery

Answer 136

Coronary artery

Answer 137

Corotid artery

Answer 138

Hepatic artery

Answer 139

Gp IIb receptor on platelet

Answer 140

Thromboxane A2

Answer 141

Fibrinogen

Answer 142

Gp Ib receptor on platelet

Answer 143

causes neutralization of phospholipid reagent in vitro

Answer 144

miscarriages are common in SLE

Answer 145

LA acts as an antibody to platelet

Answer 146

women are more commonly affected

Answer 147

followup tests include DRVVT

Answer 148

begins with excessive clotting stimulated by a substance that enters the blood

Answer 149

results in both excessive clotting and excessive bleeding

Answer 150

fibrin degradation products are generated

Answer 151

DIC is not a systemic problem, localized to specific area

Answer 152

plasminogen is consumed as it is converted into plasmin

Answer 153

increased platelets

Answer 154

schistocytes

Answer 155

PT and aPTT prolonged

Answer 156

D-dimer increased

Answer 157

Bleeding Time prolonged

Answer 158

Fibrinogen increased

Answer 159

D-dimer measures split products formed after formation of fibrin clot, but is not specific for DIC

Answer 160

Usually present in chronic conditions

Answer 161

high levels of FDPs are specific for DIC

Answer 162

none of the above

Answer 163

Bleeding Time

Answer 164

Platelet count

Answer 165

Deficiency of Thrombin

Answer 166

Deficiency of factors

Answer 167

Deficiency of Coagulation and Fibrinolytic Regulators

Answer 168

Deficiency of Vitamin K

Answer 169

Liver disease

Answer 170

Nephrotic Syndrome

Answer 171

Prolonged heparin therapy

Answer 172

all of the above

Answer 173

Protein C or Protein S deficiency

Answer 174

Factor V Leiden

Answer 175

Plasminogen deficiency

Answer 176

Antithrombin deficiency

Answer 177

A deletion in the gene sequence

Answer 178

A single adenine to guanine mutation at position 20210

Answer 179

A single guanine to adenine mutation at position 20210

Answer 180

A nonsense codon in the sequence

Answer 181

a bleeding disorder

Answer 182

an increase in fibrinolysis

Answer 183

a clotting tendency

Answer 184

decrease inhibition of tPA

Answer 185

Heparin therapy

Answer 186

Coumadin therapy

Answer 187

Prolonged for both

Answer 188

Only affects PT

Answer 189

Only affects aPTT

Answer 190

Coagulation studies

Answer 191

Aggregation studies

Answer 192

Adhesion studies

Answer 193

Fibrinogen studies

Answer 194

Fibrinogen group factors (I, V, VIII, XIII)

Answer 195

Vitamin K dependent factors (II, VII, IX, X)

Answer 196

Contact Group Factor (XII, Pre-K, HMWK)

Answer 197

TF complex (VII, TF)

Answer 198

Tissue factor

Answer 199

Phospholipid

Answer 200

Thromboplastin

Answer 201

monitors Coumadin therapy

Answer 202

screens for defects in the intrinsic and common pathways

Answer 203

requires a source of phospholipid

Answer 204

required to calculate INR

Answer 205

Kaolin is an example of a negatively charged surface needed to activate cascade

Answer 206

Tissue factor

Answer 207

extended incubation time

Answer 208

using an undiluted plasma sample

Answer 209

excess thrombin

Answer 210

fibrinogen neutralized by protamine sulphate

Answer 211

If FII levels are normal, the clot will not dissolve in 24 hours

Answer 212

If FXIII is deficient, the clot will not dissolves in 24 hours.

Answer 213

If FXIII is normal, the clot will dissolve in 24 hours.

Answer 214

If FXIII is deficient, the clot will dissolve in 24 hours.

Answer 215

Protein C is able to inactive FVa and FVIIIa

Answer 216

AT is able to inactivate FVa and FVIIIa

Answer 217

Protein C is unable to inactive FVa and FVIIIa

Answer 218

AT is unable to inactive FVa and FVIIIa

Answer 219

tests for FXIII deficiency

Answer 220

compares fibrinogen deficiency and heparin contamination

Answer 221

tests for factor antibody (eg. LA)

Answer 222

is inhibited by antithrombin

Answer 223

venom is a potent activator for FX

Answer 224

LA binds to phospholipid, inhibiting RVV

Answer 225

RVV is affected by deficiency in factors XII, XI, IX, or VIII

Answer 226

LA confirmed if DRVVT is corrected in excess phospholipid

Answer 227

FVII Deficiency

Answer 228

FVIII Deficiency

Answer 229

FX Deficiency

Answer 230

Hypofibrinogenemia

Answer 231

Both PT and aPTT

Answer 232

Fibrinogen level

Answer 233

Thrombin time

Answer 234

Dabigatran

Answer 235

Anti-platelet (ASA)

Answer 236

All of the above

Answer 237

Inactivates compound

Answer 238

Suppresses reductase activity

Answer 239

Competitively binds to Vitamin K

Answer 240

None of the above

Answer 241

Drugs that interfere with Warfarin

Answer 242

Increased Vitamin K in diet

Answer 243

Taking Warfarin pill at different times every day (not at the same time each day)

Answer 244

All of the above

Answer 245

Antithrombin III

Answer 246

Subcutaneously

Answer 247

Intravenously

Answer 248

Superficially

Answer 249

Protamine sulfate

Answer 250

Photophobia

Answer 251

Osteoporosis

Answer 252

Hypotension

Answer 253

natural drug - pentasaccharide

Answer 254

inactivates thrombin by combining with antithrombin

Answer 255

intravenous administration

Answer 256

requires lab monitoring

Answer 257

Plasma + phospholipid + calcium

Answer 258

Plasma + thromboplastin + calcium

Answer 259

Plasma + phospholipid + thromboplastin

Answer 260

Plasma + thrombin + calcium

Answer 261

Hemophilia A

Answer 262

Factor V Leiden

Answer 263

IgG binds to heparin/PF4 complex

Answer 264

leads to coagulation of platelets

Answer 265

increases platelet count

Answer 266

associated with LMWH

Answer 267

Streptokinase

Answer 268

Hemophilia A

Answer 269

Factor V Leiden

Answer 270

Dabigatran

Answer 271

Riveroxaban

Answer 272

Dabigatran

Answer 273

Argatroban

Answer 274

Bivalirudin

Answer 275

no food interactions (eg. with Vitamin K)

Answer 276

no need for routine monitoring

Answer 277

reversal of bleeding with charcoal

Answer 278

none of the above

Answer 279

all of the above

Answer 280

requires routine monitoring

Answer 281

does not need antithrombin

Answer 282

used for the prevention of thrombosis and venous thromboembolism

Answer 283

all of the above are true

Answer 284

Inhibits thrombin

Answer 285

Inhibits fibrinogen

Answer 286

Inhibits alpha granules

Answer 287

Inhibits Thromboxane A2

Answer 288

venous thrombosis

Answer 289

myocardial infarction

Answer 290

Hemophilia A

Answer 291

can be administered to any inpatient

Answer 292

Streptokinase

Answer 293

Thrombin Inhibitors

Answer 294

Streptokinase

Answer 295

All of the above are used for thrombolytic therapy

	Criado por Nadia Persaud mais de 6 anos atrás

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