1857938
Descrição
Quiz por #أطباء_2020 , atualizado more than 1 year ago
|
|
Criado por #أطباء_2020
mais de 9 anos atrás
|
|
Questão 1
Questão
what is the fate of lipid digestion products absorbed by intestinal mucosal cells?
Responda
-
export of short chain fatty acids to the portal blood
-
re-esteriification of long chain fatty acids forming triacylglycerols
-
formation of lipoprotein particles: chylomicron
-
all the above
Questão 2
Questão
after an overnight fast which of the following enzymes (proteins) show low activity?
Responda
-
glucokinase in liver
-
hexokinase in brain
-
GluT1 transporter
-
glucose 6 phosphatase in liver
-
α-ketoglutaric dehydrogenase in brain
Questão 3
Questão
which one of the following statements about prostaglandin synthesis is INCORRECT
Responda
-
Phospholipase A2 or phospholipase C release prostaglandin precursors from plasma membrane phospholipids
-
arachidonic acid is a major precursor of prostaglandins
-
Prostaglandins are derived from an essential fatty acid
-
prostaglandins are produced through the action of lipoxygenase
-
prostaglandins synthesis is inhibited by glucocorticoids and aspirin
Questão 4
Questão
uncoupling of oxidative phosphorylation could occur with
Responda
-
A high concentration of glucocorticoids
-
A high concentration of thyroxine
-
A high concentration of adrenaline
-
A high concentration of insulin
-
A high concentration of glucagon
Questão 5
Questão
sodium-glucose transporter in the intestine
Responda
-
act as symport
-
is located at the serosal side of the intestinal cell membrane
-
binds ATP
-
transport both sodium and glucose concentration gradient
Questão 6
Questão
GLUT 2 in liver cells and pancreatic β cells
Responda
-
has low Km (high affinity to glucose)
-
is suitable for glucose uptake during fasting
-
acts as glucose sensor , along with glucokinase , in β-cells of pancreas
-
all the above
Questão 7
Questão
according to Pasteur effect
Responda
-
glycolysis proceeds in a faster rate in presence of oxygen
-
oxygen decreases the rate of glycolysis
-
glycolysis produces more ATP from a glucose molecule in absence of oxygen
-
oxygen decreases the production of ATP from one glucose molecule
Questão 8
Questão
the bi-functional enzyme PFK2/fructose2,6-bisphosphatase
Responda
-
controls the level of fructose 2,6-bisphosphate ,hence the activity of PFK1
-
is phosphorylated by cAMP-dependant protein kinase under the effect of glucagon and epinephrine
-
is dephosphorylated by protein phosphatase under the effect of insulin
-
all the above
Questão 9
Questão
which of the following is true about fatty acid oxidation
Responda
-
the active form of fatty acid is fatty acyl coA
-
fatty acid is activated by acyl coA synthetase of the inner mitochondrial membrane
-
with fatty acid activation ATP is hydrolyzed to ADP + inorganic phosphate
-
Fatty acyl coA is used only for energy production
Questão 10
Questão
deficiency of carnitine acyl transferase may NOT lead to
Responda
-
failure of fatty acid oxidation
-
hypoglycemia
-
ketoacidosis
-
hepatomegaly , seizures and cardiomyopathy leading to infantile death
Questão 11
Questão
mitochondrial β-oxidation pathway produces propionyl CoA from
Responda
-
fatty acid with odd number of carbons
-
phytanic acid derived from chlorophyll
-
both (A) & (b)
-
neither (A) nor (B)
Questão 12
Questão
Zellweger's (cerebro-hepato-renal) syndrome is characterizd by accumulation
Responda
-
phytanic acid
-
very long chain polyenoic acid
-
both (A) & (B)
-
neither (A) nor (B)
Questão 13
Questão
ِAn enzyme is not involved in glycolysis in muscle is
Responda
-
aldolase
-
glyceraldehyde 3-phosphate dehydrogenase
-
enolase
-
pyruvate kinase
-
bisphosphoglycerate mutase
Questão 14
Questão
the best description of the difference between glucokinase and hexokinase is
Responda
-
hexokinase is found in liver and kidney , while hexokinase is present in nearly all tissues
-
hexokinase has much higher Km for glucose
-
glucokinase is found only in tissues that are totally dependent on glucose for fuel , such as brain & RBCs
-
glucokinase & hexokinase are zymogens
-
glucokinase but not hexokinase is induced by insulin
Questão 15
Questão
An abnormal accumulation of galactose 1-p in liver is usually caused by a deficiency
Responda
-
glucose 6-phosphate dehydrogenase
-
glucose 6-phosphatse
-
galactokinase
-
galactose 1-phosphate uridylyl transferase
-
hexokinase
Questão 16
Questão
the oxidative decarboxylation of all α-keto acids is similar to that of pyruvate. A common requirment for all is
Responda
-
NADP
-
Acetyl CoA
-
Lipoic acid
-
α -ketoglutarate
-
GDP
Questão 17
Questão
mitochondria in brown fat of human infants increase heat generation .this result from an increased rate of electron transport due to
Responda
-
inhibition of ADP-ATP antiporter
-
inhibition of F1-Fo ATP synthase
-
blockage of NADH reoxidation
-
increased permeability of the inner mitochondrial membrane
-
decreased rate of oxygen consumption
Questão 18
Questão
all the electron carrying groups of the respiratory chain
Responda
-
are fixed to the inner mitochondrial membrane
-
are arranged in an order of descending redox potential
-
contain iron as an electron acceptor
-
participate in the building up of the proton gradient
-
none of the above
Questão 19
Questão
the following enzyme is a constituent of pentose phosphate pathway
Responda
-
glucose 6-phosphatase
-
phosphorylase
-
hexokinase
-
glucose 6-phosphate dehydrogenase
-
phosphohexoisomerase
Questão 20
Questão
a substance that is not an intermediate in formation of glucuronic acid from glucose
Responda
-
UDP-galactose
-
UDP-glucose
-
Glucose 6-phosphate
-
UDP-glucuronic acid
-
glucose 1-phosphate
Questão 21
Questão
in the break down of muscle glycogen the predominant product is
Responda
-
glucose
-
glucose 1-phosphate
-
UDP-glucose
-
maltose
-
maltriose
Questão 22
Questão
the regulation of glycogenolysis in muscle differ from that in the liver
Responda
-
muscles lack receptors of glucagon
-
only the liver uses β-adrenergic receptors for this regulation
-
only muscles respond to epinephrine
-
muscle glycogenolysis does not respond to stimulation by intracellular calcium
-
muscle produces mostly glucose from glycogen
Questão 23
Questão
mammalian fatty acids desaturase systems introduce double bonds
Responda
-
at Δ4, Δ5, Δ6, Δ9 positions
-
at ω3, ω6 and ω9 positions
-
between an existing double bond and methyl carbon
-
all the above
Questão 24
Questão
lypolysis in adipose tissue is initiated by
Responda
-
Food intake
-
ketoacidosis
-
fasting
-
high insulin/glucagon ratio
-
high fatty acid concentration
Questão 25
Questão
The enzyme required for both the synthesis of acetoacetate and its utilization as a fuel is
Responda
-
succinyl coA : acetoacetate CoA transferase
-
HMG-CoA synthase
-
thiolase
-
HMG-CoA lyase
-
β-hydroxybutyrate dehydrogenase
Questão 26
Questão
Receptor-mediated uptake of excess LDL results in all the following Except
Responda
-
increased estrification of cholesterol
-
increased production of mevalonate
-
decreased synthesis of HMG-CoA reductase
-
decreased synthesis of the LDL recepttor
-
decreased receptor-mediated endocytosis of LDL
Questão 27
Questão
In man serum lipoprotein fraction with the highest cholesterol content is
Responda
-
α-lipoprotein
-
β-lipoprotein
-
pre β-lipoprotein
-
chylomicrons
-
pre-albumin
Questão 28
Questão
secondary bile acids are distinguishable from the primary bile acids because they lack
Responda
-
glycine
-
taurine
-
a hydroxyl group
-
a methyl group
-
a carboxylate group
Questão 29
Questão
what is the enzyme used for cholesterol storage
Responda
-
HMG-CoA reductase
-
Lecithin cholesterol acyl transferase
-
lipoprotein lipase
-
Acyl CoA cholesterol acyl transferase
-
cholesterol esterase
Questão 30
Questão
cori cycle transfers
Responda
-
alanine from muscle to liver
-
lactic from liver to muscle
-
lactic from exercising muscle or RBCs to liver
-
Glucose from muscle to liver
Quer criar seus próprios Quizzes gratuitos com a GoConqr? Saiba mais.