Growth Factors

Descrição

Structural Basis for Biological Function (Basics) Quiz sobre Growth Factors, criado por gina_evans0312 em 04-11-2013.
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Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312 mais de 10 anos atrás
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Resumo de Recurso

Questão 1

Questão
Epidermal Growth Factors are 53aa long, with an Mr of 40,000
Responda
  • True
  • False

Questão 2

Questão
What happens when you increase ornithine carboxylase and polyamine concentrations?
Responda
  • Cell division increases
  • Cell division decreases

Questão 3

Questão
In general effects ( inc glucose/aa transport and inc Na/K ATPase activity) what hormone are growth factors most like?
Responda
  • Insulin
  • Glucagon
  • Vasopressin
  • NO

Questão 4

Questão
Increase Na+/H+ pump activity causes what?
Responda
  • Alkylysation of the cytoplasm
  • Inc. DNA synthesis/mitosis
  • Inc protein production

Questão 5

Questão
How is tyrosine kinase kept inactive when a ligand is not bound?
Responda
  • The activation lip hides the active site
  • The active site is phosphorylated and inactive
  • A pseudosubstrate is bound

Questão 6

Questão
What form does inactive tyrosine kinase stay in?
Responda
  • Monomer
  • Dimer
  • Multimeric group

Questão 7

Questão
What effect does ligand binding have to tyrosine kinase?
Responda
  • Partial activation
  • Dimerisation
  • Monomerisation
  • Full activation

Questão 8

Questão
Once the activation lip is phosphorylated, what happens?
Responda
  • Phosphorylation continues of tyrosine kinase
  • Becomes fully active
  • Becomes partially active
  • Proteins bind to phosphorylated areas

Questão 9

Questão
Which of the following binds to phosphorylated tyrosine kinase?
Responda
  • GRB2
  • RAs
  • GEF

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