Quiz
BioMed II Exam 2
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1A mature adult has around ____________ cells.
- A60 Trillion
- B50 Trillion
- C100 Trillion
- D10 Trillion
2There are [blank_start]300[blank_end] different cell types in a normal human body, however, there are [blank_start]301[blank_end] different cell types in someone who has developed cancer.
- A300
- B301
3Proliferation is used for:
- AGrowth
- BApoptosis
- CReplenishment
- DNecrosis
4On average, _________ cells die and replenish every second.
- A10 million
- B15 million
- C2 million
- D5 million
5Which of these cell types have a "lifetime" longevity?
- ASkin Cells
- BBone Cells
- CNeurons
- DMuscle Cells
- ESpermatozoa
- FOocytes
6Match the method of cell death with its definition.
[blank_start]Apoptosis[blank_end] --> The cell agrees to kill itself due to medium damage.
[blank_start]Necrosis[blank_end] --> The cell is killed due to extreme damage.
[blank_start]Senescence[blank_end] --> The cell agrees to stop replicating due to small damage.- ANecrosis
- BApoptosis
- CSenescence
- DApoptosis
- ENecrosis
- FSenescence
- GSenescence
- HApoptosis
- INecrosis
7In the word Apoptosis. "apo" means [blank_start]near[blank_end] and "ptosis" means [blank_start]drooping[blank_end].
- Anear
- Bdrooping
8Organize the differences between Necrosis and Apoptosis.
Necrosis:
- Death of [blank_start]Healthy[blank_end] Cells
- [blank_start]Premature[blank_end] Death
- [blank_start]Lots[blank_end] of chemicals and invading microbes
- Very [blank_start]Fast[blank_end] death
- [blank_start]"Kill and Spill"[blank_end]
- [blank_start]Inflammation[blank_end] Response
Apoptosis:
- Death of [blank_start]Unhealthy[blank_end] Cells
- [blank_start]Natural[blank_end] Death
- [blank_start]Small amounts[blank_end] of chemicals and invading microbes
- Very [blank_start]Slow[blank_end] Death
- [blank_start]"Tag and Bag"[blank_end]
- [blank_start]Minimal[blank_end] Response- AHealthy
- BUnhealthy
- CPremature
- DNatural
- ELots
- FSmall Amounts
- GFast
- HSlow
- I"Kill and Spill"
- J"Tag and Bag"
- KInflammation
- LMinimal
- MUnhealthy
- NHealthy
- ONatural
- PPremature
- QSmall amounts
- RLots
- SSlow
- TFast
- U"Tag and Bag"
- V"Kill and Spill"
- WMinimal
- XInflammation
9Old and Damaged cells are replenished by what type of cells?
- ABone Marrow Cells
- BStem Cells
- CBlood Cells
- DThey are not replenished
10[blank_start]Stem[blank_end] cells are considered "Immortal".
[blank_start]Progenitor[blank_end] cells are considered "Mortal".
[blank_start]Mature[blank_end] Cells are "Terminal".- AStem
- BProgenitor
- CMature
11All tissues have stem cells.
- AVerdadeiro
- BFalso
12Similarities between Stem cells and Tumor Cells include:
- AHigh Proliferation Rates
- BPotential to Migrate
- CCan remain Quiescent for long periods of time
- DResistant to Apoptosis
- EResistant to Toxin Infiltration
13The most common cause of tumors are genetic changes in DNA.
- AVerdadeiro
- BFalso
14[blank_start]Deletions and Duplications[blank_end] change the number of genes which results in excessive or dysfunctional production of proteins.
[blank_start]Mutations[blank_end] result in a change in sequence and function and can be hereditary or acquired over time.
[blank_start]Epigenetic changes[blank_end] happen when something latches onto the gene or DNA sequence changing the functionality- ADeletions and Duplications
- BMutations
- CEpigenetic Changes
- DMutations
- EDeletions and Dupications
- FEpigenetic Changes
- GEpigenetic changes
- HMutations
- IDeletions and Duplications
15If someone does not have Cancer, they do not have any tumor causing mutations within their DNA.
- AVerdadeiro
- BFalso
16Mutations can be Inherited or Acquired over time.
- AVerdadeiro
- BFalso
17[blank_start]Malignant Tumors[blank_end] spread to other tissues while [blank_start]Benign Tumors[blank_end] remain within a specific connective tissue area.
- AMalignant Tumors
- BBenign Tumors
- CBenign Tumors
- DMalignant Tumors
18The zodiac sign "Cancer" was named such based off of the fact that "Cancer" the disease resembled a crab.
- AVerdadeiro
- BFalso
19What determines the difference between a Benign tumor and a Malignant tumor is the number and type of mutations.
- AVerdadeiro
- BFalso
20Benign Tumors are completely harmless.
- AVerdadeiro
- BFalso
21Problems that can be caused by benign tumors include:
- ADirect Physical Problems
- BIndirect Physical Problems
- CChemical Problems
- DCosmetic Concerns
- EBenign Tumors are Harmless and Do Not cause Problems
22Any abnormal mass is considered a tumor.
- AVerdadeiro
- BFalso
23Moles always form before Adulthood.
- AVerdadeiro
- BFalso
24What type of benign tumor is the most common to arise during adulthood?
- APapilloma
- BOsteoma
- CLipoma
- DMyoma
25What percentage of malignant tumors are inherited?
- A20%
- B25%
- C30%
- D15%
26Some cancers are more inheritable than others.
- AVerdadeiro
- BFalso
27Gene mutations can be acquired from:
- ARadiation
- BViruses
- CCarcinogens
- DPhytochemicals
- EChronic Inflammation
28The top 4 viral causes of cancer in order are:
1. [blank_start]Human Papilloma Virus (HPV)[blank_end]
2. [blank_start]Hepatitis B Virus (HBV)[blank_end]
3. [blank_start]Hepatitis C Virus (HCV)[blank_end]
4. [blank_start]Epstein-Barr Virus (EBV)[blank_end]- AHuman Papilloma Virus (HPV)
- BHepatitis B Virus (HBV)
- CHepatitis c Virus (HCV)
- DEpstein-Barr Virus (EBV)
- EHepatitis B Virus (HBV)
- FHuman Papilloma Virus (HPV)
- GHepatitis C Virus (HCV)
- HEpstein-Barr Virus (EBV)
- IHepatitis C Virus (HCV)
- JEpstein-Barr Virus (EBV)
- KHepatitis B Virus (HBV)
- LHuman Papilloma Virus (HPV)
- MEpstein-Barr Virus (EBV)
- NHuman Papilloma Virus (HPV)
- OHepatitis B Virus (HBV)
- PHepatitis C Virus (HCV)
29Cells that replicate more are more at risk to form Cancer.
- AVerdadeiro
- BFalso
30Put the steps of cell replication initiation in order:
1. [blank_start]Ligand[blank_end]
2. [blank_start]Receptor[blank_end]
3. [blank_start]Signaling Molecules[blank_end]
4. [blank_start]Cell Cycle Progression[blank_end]
5. [blank_start]Cell Replication[blank_end]- ALigand
- BReceptor
- CSignaling Molecules
- DCell Cycle Progression
- ECell Replication
31Excess production of which proteins result in excess cell proliferation?
- ABRCA
- BEGF
- CHER2
- Dp53
- ERas
32Proto-oncogene stands for "Early Cancer Gene" because the normal version of this gene can be mutated into a cancer causing gene.
- AVerdadeiro
- BFalso
33Increasing the amount of HER2 receptors in a cell increases the amount of signals being sent which then decreases the rate of cell proliferation.
- AVerdadeiro
- BFalso
34When there is a small amount of DNA damage detected, which proteins are activated to inhibit the cell cycle progression?
- AP16
- BBRCA
- Cp53
- DHER2
- ERas
35When there is a small amount of DNA damage detected and the cell cycle is paused, which proteins start repairing the damaged DNA?
- AP16
- BBRCA
- Cp53
- DHER2
- ERas
36When a large amount of DNA damage is detected, which proteins are activated to induce apoptosis?
- AP16
- BBRCA
- Cp53
- DHER2
- ERas
37The most mutated gene in all cancers is:
- AP16
- BBRCA
- Cp53
- DHER2
- ERas
38The [blank_start]primary[blank_end] site is the origin of the tumor while the [blank_start]secondary[blank_end] site is where the tumor has traveled to.
- Aprimary
- Bsecondary
39Cancer cells travel through the [blank_start]blood[blank_end] or [blank_start]lymph[blank_end] vessels.
- Ablood
- Blymph
40Metastasis relies on more [blank_start]replication[blank_end] and less [blank_start]apoptosis[blank_end] of cells.
- Areplication
- Bapoptosis
41The steps of Metastasis in order:
1. [blank_start]More Replication & Less Apoptosis[blank_end]
2. [blank_start]Evasion[blank_end]
3. [blank_start]Loss of Contact Inhibition[blank_end]
4. [blank_start]Angiogenesis[blank_end]
5. [blank_start]Emigration[blank_end]
6. [blank_start]Immigration[blank_end]- AMore Replication & Less Apoptosis
- BEvasion
- CLoss of Contact Inhibition
- DAngiogenesis
- EEmigration
- FImmigration
42Cancer cells tend to invade tissues similar to their primary site tissues.
- AVerdadeiro
- BFalso
43Match the 5 Major Types of Cancer with their definitions.
[blank_start]Carcinomas[blank_end] --> Cancer of the Epithelial Cells
[blank_start]Melanomas[blank_end] --> Cancer of Melanocytes
[blank_start]Sarcomas[blank_end] --> Cancer of the Connective Tissues
[blank_start]Myeloid Leukemia[blank_end] --> Cancer of Mast, Baso, Eosin, Neutro, or Monocytes
[blank_start]Lymphoid Leukemia[blank_end] --> Cancer of the Lymphocytes- ACarcinomas
- BMelanomas
- CSarcomas
- DMyeloid Leukemia
- ELymphoid Leukemia
- FMelanomas
- GCarcinomas
- HSarcomas
- IMyeloid Leukemia
- JLymphoid Leukemia
- KSarcomas
- LCarcinomas
- MMelanomas
- NMyeloid Leukemia
- OLymphoid Leukemia
- PMyeloid Leukemia
- QCarcinomas
- RMelanomas
- SSarcomas
- TLymphoid Leukemia
- ULymphoid Leukemia
- VCarcinomas
- WMelanomas
- XSarcomas
- YMyeloid Leukemia
44All of these can be symptoms of cancer EXCEPT
- ADyspnea
- BSeizures
- CHemoptysis
- DLymphedema
- EJaundice
- FAll of these can be symptoms of Cancer
45A Patient experiencing a tumor in the bone marrow may have symptoms such as...
- AFatigue
- BVertigo
- CBleeding
- DInfections
46Cancer is consistently considered the [blank_start]2nd[blank_end] most common cause of death in the US.
- A2nd
- B1st
- C3rd
47Tumors are detectable before they become a critical mass.
- AVerdadeiro
- BFalso
48A biopsy is considered the "[blank_start]gold standard[blank_end]" for tumor diagnosis.
- Agold standard
49Tumor Detection Involves which of the following:
- AVisualization & Palpitation
- BImaging & Observing
- CTesting
- DSampling
- EAll of the Above
50In Antineoplastic surgery, Combotherapy can involve a combination of [blank_start]Surgery[blank_end], [blank_start]Radiation[blank_end], and [blank_start]Chemotherapy[blank_end].
- ASurgery
- BRadiation
- CChemotherapy
51[blank_start]Surgery and Radiation[blank_end] are usually used in early stage cancers while [blank_start]Chemotherapy[blank_end] is used in advanced stage cancers.
- ASurgery and Radiation
- BChemotherapy
- CChemotherapy
- DSurgery and Radiation
52Match the surgery type with its goal:
[blank_start]Curative[blank_end] --> Removing all of the tumor to cure the patient
[blank_start]Debulking[blank_end] --> Removing a large amount of the tumor to improve the prognosis of the cancer
[blank_start]Palliative[blank_end] --> Removing some of the tumor to increase the comfort and quality of life for the patient- ACurative
- BDebulking
- CPalliative
- DDebulking
- ECurative
- FPalliative
- GPalliative
- HCurative
- IDebulking
53The general methods that chemotherapy uses to inhibit cellular replication and increase apoptosis include:
- AInhibiting Hormone and Secreted Molecules
- BInhibiting Kinases and Phosphate Groups
- CUsing Surface Molecules and Damaging the DNA
- DInhibiting DNA Replication and Chromosome Separation
54Two Chemotherapeutic Hormone inhibitors mentioned were [blank_start]Tamoxifen[blank_end] and [blank_start]Bicalutamide[blank_end].
- ATamoxifen
- BBicalutamide
55Replicating Cells secrete [blank_start]VEGF[blank_end] to stimulate the growth of blood vessels towards them to deliver Oxygen and Glucose
- AVEGF
56An example of a medication that is a Monoclonal Antibody (MAB) targeting secreted molecules is:
- ABevacizumab (Avastin)
- BBendamustine (Bendeka)
- CAltretamine (Hexalen)
- DDoxorubicin (Adriamycin)
57An example of a medication that is a Monoclonal Antibody (MAB) targeting surface molecules is:
- ATrastuzumab (Herceptin)
- BBendamustine (Bendeka)
- CAltretamine (Hexalen)
- DDoxorubicin (Adriamycin)
58A medication that is an example of a chemotherapeutic kinase inhibitor is:
- AImatinib (Gleevec)
- Bifosfamide (Ifex)
- CTrastuzumab (Herceptin)
- DBevacizumab (Avastin)
59Which of these are Alkylating/Alkylating-like Agents?
- ACyclophosphamide
- BCisplatin
- CChlorambucil
- DI and II
- EII and III
60Which of these are an Antimetabolite Drug?
- AMethotrexate
- BMercaptopurine
- CPrednisone
- D5-Flurouracil
61Which of these are a Topoisomerase Inhibitor?
- AIrinotecan
- BEtoposide
- CCisplatin
- DBendamustine
62Which of these are Antimitoic Agents?
- AVincristine
- BPaclitaxel
- CCyclophospamide
- DDexamethasone
63[blank_start]Primary[blank_end] Drug resistance is when Cancer is resistant to a drug before exposure.
[blank_start]Acquired[blank_end] Drug resistance is when the Cancer becomes resistant over time after exposure.- APrimary
- BAcquired
64Systematic chemotherapy administration involves:
- AIntravenous Chemo
- BOral Chemo
- CSubcutaneous Chemo
- DIntramuscular Chemo
- EIntradermal Cheo
65Local chemotherapy administration methods mentioned include:
- AIntrathecal
- BIntravesical
- CIntravenous
- DIntramuscular
66Drugs injected via I.V. cross BBB into the Central Nervous System.
- AVerdadeiro
- BFalso
67Continuous Chemotherapy treatment is considered [blank_start]Rare[blank_end] while Noncontinuous treatment is [blank_start]More Common[blank_end].
- ARare
- BMore Common
- CMore Common
- DRare
68Noncontinuous treatment consists of weeks of treatment and then a few days of no treatment for the healthy cells to recover.
- AVerdadeiro
- BFalso
69Match the Chemotherapy response with its definition:
[blank_start]Complete Response[blank_end] --> 100% disappearance after 1 month of treatment
[blank_start]Partial Response[blank_end] --> 30% or greater decrease in tumor diameter along with no new disease
[blank_start]Stable Disease[blank_end] --> Tumor has no change in size
[blank_start]Progressive Disease[blank_end] --> 20% or greater increase in tumor size or Tumor has spread- AComplete Response
- BPartial Response
- CStable Disease
- DProgressive Disease
- EPartial Response
- FComplete Response
- GStable Disease
- HProgressive Disease
- IStable Disease
- JComplete Response
- KPartial Response
- LProgressive Disease
- MProgressive Disease
- NStable Disease
- OComplete Response
- PPartial Response
70The 1st FDA approved gene therapy mentioned was [blank_start]CAR-T[blank_end] therapy.
- ACAR-T
71The Top 4 Modifiable Risk Factors for Cancer in Order are:
1. [blank_start]Cigarette Smoking[blank_end]
2. [blank_start]Excess Weight[blank_end]
3. [blank_start]Alcohol Intake[blank_end]
4. [blank_start]UV Exposure[blank_end]- ACigarette Smoking
- BExcess Weight
- CAlcohol Intake
- DUV Exposure
- EAlcohol Intake
- FCigarette Smoking
- GExcess Weight
- HUV Exposure
- IExcess Weight
- JCigarette Smoking
- KAlcohol Intake
- LUV Exposure
- MUV Exposure
- NCigarette Smoking
- OExcess Weight
- PAlcohol Intake
72Pro-inflammation promotes Cancer.
- AVerdadeiro
- BFalso
Informações
- Descrição
- Lectures Neoplasia I and II
- Autor
- Monica Werner
- Idioma
- English
- Visualizações
- 52
- Etiquetas
- Avaliação
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