Flashcards
Blood Products - Absite
Flashcards do conjunto (28)
- 1Blood products that don't carry a risk of HIV or hepatitisAlbumin and serum globulins
- 2What is donated blood screened for?HIV, HepB, HepC, HTLV, syphilis, West Nile virus
- 3Who do you use CMV negative blood on?use in low-birth weight infants
BM transplant patients
Other transplant patients - 4Universal Blood Donor, Blood typeType O, contains no antigens
- 5What type of blood should females of childbearing age receive if need blood products?Rh-negative blood
- 6Bohr Effect on Stored Bloodlow in 2,3-DPG causing a left shift
increased affinity for oxygen - 7Type and Crossmatchdetermines ABO compatibility
- 8Type and Screendetermines ABO compatibility and looks for preformed Ab's to minor antigens
- 9How much does 1U of pRBC raise Hb and Hct by?1UpRBC increases Hb by 1 and Hct by 3-5
- 10One 6pack of Platelets should increase platelet count by how much?50,000
- 11Acute Hemolysis its cause, type of hypersensitivity, symptomsFrom ABO incompatibility
Type II HS
Back pain, chills, tachycardia,fever, hemoglobinuria - 12Effects of acute hemolysis on Haptoglobin, free Hb, unconjugated bilirubinHaptoglobin <50mg/dL
Free Hb >5g/dL
Increase in unconjugated bilirubin - 13Treatment for Acute Hemolysisfluids, diuretics, HCO3, pressors
- 14What is delayed hemolysis and what is its treatment?mild jaundice
antibody mediated against minor antigens from donor
Tx: observe if stable - 15What is non-immune hemolysis? How to treat?from squeezed blood
tx: fluids and diuretics - 16MC transfusion reactionFebrile nonhemolytic transfusion reaction
- 17Cause of febrile nonhemolytic transfusion reactionrecipient antibody reaction against donor WBC (cytokine release)
- 18Treatment for febrile nonhemolytic transfusion reactiond/c transfusion + antipyretics (not aspirin)
use WBC filters for subsequent transfusions - 19Cause of urticaria during blood transfusionsnonhemolytic
recipient antibodies against donor plasma proteins or IgA in an IgA deficient pt - 20Treatment of Urticaria during blood transfusionsbenadryl, supportive treatment
- 21Anaphylaxis during blood transfusions symptoms and why it occursbronchospasm, HoTN, angioedema, urticaria
Recipient Abs against donor IgA in IgA deficient patient - 22Treatment for anaphylaxisEpinephrine, fluids, pressors, steroids, histamine blockers like Benadryl
- 23Transfusion-related acute lung injury (TRALI)caused by donor antibodies to recipient's WBCs, clot in pulm capillaries
Leads to ARDS in <6hrs
MCC of death from transfusions - 24How does the cold affect blood transfusions?coagulopathy due to slowing of enzyme reactions
- 25How Hypocalcemia affect blood transfusionscan cause poor clotting as it is required for clotting cascade
Seen with massive transfusions - 26How Citrate affects blood productsbinds calcium after transfusion and causes hypocalcemia
- 27Most common bacterial contaminate in blood transfusionsGNRs, usually E. coli
- 28Most common blood product source of contaminationPlatelets, because they are not refrigerated
Informações
- Descrição
- Surgery - Absite Review FlashCards sobre Blood Products - Absite, criado por Jennifer Huber em 30-05-2018.
- Criado por
- Jennifer Huber
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